Evidence map›Paper›PMID 36829768›Full record

ArticleBioengineering (Basel, Switzerland)2023

An In Vivo Rat Study of Bioresorbable Mg-2Zn-2Ga Alloy Implants.

Alexey Drobyshev, Zaira Gurganchova, Nikolay Redko, Alexander Komissarov, Viacheslav Bazhenov, Eugene S Statnik, Iuliia A Sadykova, Eugeny Sviridov, Alexey I Salimon, Alexander M Korsunsky and 3 more

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Alexey DrobyshevLaboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia.
Zaira GurganchovaLaboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia.ORCID 0000-0003-2719-3327
Nikolay RedkoLaboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia.ORCID 0000-0001-7807-9351
Alexander KomissarovLaboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia.ORCID 0000-0001-5125-9870
Viacheslav BazhenovCasting Department, National University of Science and Technology "MISiS", 119049 Moscow, Russia.ORCID 0000-0003-3214-1935
Eugene S StatnikHSM Laboratory, Center for Digital Engineering, Skoltech, 121205 Moscow, Russia.ORCID 0000-0002-1105-9206
Iuliia A SadykovaHSM Laboratory, Center for Digital Engineering, Skoltech, 121205 Moscow, Russia.
Eugeny SviridovLaboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia.
Alexey I SalimonHSM Laboratory, Center for Digital Engineering, Skoltech, 121205 Moscow, Russia.ORCID 0000-0002-9048-8083
Alexander M KorsunskyHSM Laboratory, Center for Digital Engineering, Skoltech, 121205 Moscow, Russia.ORCID 0000-0002-3558-5198
Oleg ZayratyantsLaboratory of the Clinical Medical Center, Moscow State University of Medicine and Dentistry, 111398 Moscow, Russia.
Denis UshmarovEducational and Production Department, Kuban State Medical University, 350912 Krasnodar, Russia.
Oleg YanushevichLaboratory of Medical Bioresorption and Bioresistance, Moscow State University of Medicine and Dentistry, 127473 Moscow, Russia.
Moscow State University of Medicine and Dentistry · RUSkolkovo Institute of Science and Technology · RUNational University of Science and Technology · RUKuban State Medical University · RU

Funding

Ministry of Science and Higher Education of the Russian Federation 1
6 · The paper itself

Abstract

In the present study, pins made from the novel Mg-2Zn-2Ga alloy were installed within the femoral bones of six Wistar rats. The level of bioresorption was assessed after 1, 3, and 6 months by radiography, histology, SEM, and EDX. Significant bioresorption was evident after 3 months, and complete dissolution of the pins occurred at 6 months after the installation. No pronounced gas cavities could be found at the pin installation sites throughout the postoperative period. The animals' blood parameters showed no signs of inflammation or toxication. These findings are sufficiently encouraging to motivate further research to broaden the experimental coverage to increase the number of observed animals and to conduct tests involving other, larger animals.

Indexed as

bioresorbable materialsbioresorptionmagnesium alloys

Identifiers

PMID36829768
PMCPMC9952904
OpenAlexW4321371584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.