Influence of Inlet Boundary Conditions on the Prediction of Flow Field and Hemolysis in Blood Pumps Using Large-Eddy Simulation.

Wen-Jing Xiang, Jia-Dong Huo, Wei-Tao Wu, Peng Wu

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Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Wen-Jing XiangArtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou 215000, China.

Jia-Dong HuoArtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou 215000, China.

Wei-Tao WuSchool of Mechanical Engineering, Nanjing University of Science and Technology, Nanjing 210095, China.

Peng WuArtificial Organ Technology Laboratory, School of Mechanical and Electric Engineering, Soochow University, Suzhou 215000, China.

Funding

National Natural Science Foundation of China Nos. 12072216Natural Science Foundation of Jiangsu Province BK20201302the Mobility Program of the Sino-German Center No. M-0231

6 · The paper itself

Abstract

Inlet boundary conditions (BC) are one of the uncertainties which may influence the prediction of flow field and hemolysis in blood pumps. This study investigated the influence of inlet BC, including the length of inlet pipe, type of inlet BC (mass flow rate or experimental velocity profile) and turbulent intensity (no perturbation, 5%, 10%, 20%) on the prediction of flow field and hemolysis of a benchmark centrifugal blood pump (the FDA blood pump) and a commercial axial blood pump (Heartmate II), using large-eddy simulation. The results show that the influence of boundary conditions on integral pump performance metrics, including pressure head and hemolysis, is negligible. The influence on local flow structures, such as velocity distributions, mainly existed in the inlet. For the centrifugal FDA blood pump, the influence of type of inlet BC and inlet position on velocity distributions can also be observed at the diffuser. Overall, the effects of position of inlet and type of inlet BC need to be considered if local flow structures are the focus, while the influence of turbulent intensity is negligible and need not be accounted for during numerical simulations of blood pumps.

Indexed as

blood pumpCFDflow fieldhemolysisinlet boundary conditionturbulent intensity

Identifiers

PMID36829767

DOI10.3390/bioengineering10020274

PMCPMC9952191

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