ArticleBioengineering (Basel, Switzerland)2023
The Effect of Blood Rheology and Inlet Boundary Conditions on Realistic Abdominal Aortic Aneurysms under Pulsatile Flow Conditions.
Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed.
- Position-Dependent Hemodynamics of Popliteal Artery Stent Grafts: The POPFLEX Study.Methods and protocols · 2026Article
- Integrated Assessment of Wall Shear Stress-Related Hemodynamic Parameters in Abdominal Aortic Aneurysms: A Retrospective Cross-Sectional Study on Ruptured Cases.International journal for numerical methods in biomedical engineering · 2026Article
- Time-dependent simulation of blood flow through an abdominal aorta with iliac arteries.European biophysics journal : EBJ · 2024Article
- Computational Modeling Approach to Profile Hemodynamical Behavior in a Healthy Aorta.Bioengineering (Basel, Switzerland) · 2024Article
- On the feasibility of ultrasound Doppler-based personalized hemodynamic modeling of the abdominal aorta.Biomedical engineering online · 2024Article
- Selection of Bifurcated Grafts' Dimensions during Aorto-Iliac Vascular Reconstruction Based on Their Hemodynamic Performance.Bioengineering (Basel, Switzerland) · 2023Article
- Effect of Intraluminal Thrombus Burden on the Risk of Abdominal Aortic Aneurysm Rupture.Journal of cardiovascular development and disease · 2023Article
- Intraluminal Thrombus Characteristics in AAA Patients: Non-Invasive Diagnosis Using CFD.Bioengineering (Basel, Switzerland) · 2023Article
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4 authors.
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Abstract
backgroundThe effects of non-Newtonian rheology and boundary conditions on various pathophysiologies have been studied quite extensively in the literature. The majority of results present qualitative and/or quantitative conclusions that are not thoroughly assessed from a statistical perspective.
methodsThe finite volume method was employed for the numerical simulation of seven patient-specific abdominal aortic aneurysms. For each case, five rheological models and three inlet velocity boundary conditions were considered. Outlier- and heteroscedasticity-robust ANOVA tests assessed the simultaneous effect of rheological specifications and boundary conditions on fourteen variables that capture important characteristics of vascular flows.
resultsThe selection of inlet velocity profiles appears as a more critical factor relative to rheological specifications, especially regarding differences in the oscillatory characteristics of computed flows. Response variables that relate to the average tangential force on the wall over the entire cycle do not differ significantly across alternative factor levels, as long as one focuses on non-Newtonian specifications.
conclusionsThe two factors, namely blood rheological models and inlet velocity boundary condition, exert additive effects on variables that characterize vascular flows, with negligible interaction effects. Regarding thrombus-prone conditions, the Plug inlet profile offers an advantageous hemodynamic configuration with respect to the other two profiles.
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