Evidence map›Paper›PMID 36829761›Full record

ArticleBioengineering (Basel, Switzerland)2023

K2S Challenge: From Undersampled K-Space to Automatic Segmentation.

Aniket A Tolpadi, Upasana Bharadwaj, Kenneth T Gao, Rupsa Bhattacharjee, Felix G Gassert, Johanna Luitjens, Paula Giesler, Jan Nikolas Morshuis, Paul Fischer, Matthias Hein and 13 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Artificial intelligence in musculoskeletal applications: a primer for radiologists.Diagnostic and interventional radiology (Ankara, Turkey) · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Synthetic Knee MRI TBioengineering (Basel, Switzerland) · 2023
    Article
  10. AI for PET image reconstruction.The British journal of radiology · 2023
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Aniket A TolpadiDepartment of Bioengineering, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-3974-4838
Upasana BharadwajDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0002-4710-809X
Kenneth T GaoDepartment of Bioengineering, University of California, Berkeley, CA 94720, USA.
Rupsa BhattacharjeeDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA.ORCID 0000-0001-9893-3527
Felix G GassertDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA.
Johanna LuitjensDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA.
Paula GieslerDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA.
Jan Nikolas MorshuisCluster of Excellence Machine Learning, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-3481-4008
Paul FischerCluster of Excellence Machine Learning, University of Tübingen, 72076 Tübingen, Germany.
Matthias HeinCluster of Excellence Machine Learning, University of Tübingen, 72076 Tübingen, Germany.
Christian F BaumgartnerCluster of Excellence Machine Learning, University of Tübingen, 72076 Tübingen, Germany.
Artem RazumovCenter for Computational and Data-Intensive Science and Engineering, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.
Dmitry DylovCenter for Computational and Data-Intensive Science and Engineering, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.ORCID 0000-0003-2251-3221
Quintin van LohuizenDepartment of Radiology, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-7128-0818
Stefan J FransenDepartment of Radiology, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-5454-5052
Xiaoxia ZhangCenter for Advanced Imaging Innovation and Research, New York University Grossman School of Medicine, New York, NY 10016, USA.
Radhika TibrewalaCenter for Advanced Imaging Innovation and Research, New York University Grossman School of Medicine, New York, NY 10016, USA.
Hector Lise de MouraCenter for Advanced Imaging Innovation and Research, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-6620-9814
Kangning LiuCenter for Advanced Imaging Innovation and Research, New York University Grossman School of Medicine, New York, NY 10016, USA.
Marcelo V W ZibettiCenter for Advanced Imaging Innovation and Research, New York University Grossman School of Medicine, New York, NY 10016, USA.ORCID 0000-0003-2856-3625
Ravinder RegatteCenter for Advanced Imaging Innovation and Research, New York University Grossman School of Medicine, New York, NY 10016, USA.
Sharmila MajumdarDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA.
Valentina PedoiaDepartment of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94158, USA.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Daniel K Sodickson · 2014 to 2026
$19.3M
Ultra-Fast Knee MRI with Deep LearningR01AR078762 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MAJUMDAR, SHARMILA · 2021 to 2025
$2.8M
NIAMS NIH HHS R01 AR078762NIBIB NIH HHS P41 EB017183NIH HHS R01AR078762
6 · The paper itself

Abstract

Magnetic Resonance Imaging (MRI) offers strong soft tissue contrast but suffers from long acquisition times and requires tedious annotation from radiologists. Traditionally, these challenges have been addressed separately with reconstruction and image analysis algorithms. To see if performance could be improved by treating both as end-to-end, we hosted the K2S challenge, in which challenge participants segmented knee bones and cartilage from 8× undersampled k-space. We curated the 300-patient K2S dataset of multicoil raw k-space and radiologist quality-checked segmentations. 87 teams registered for the challenge and there were 12 submissions, varying in methodologies from serial reconstruction and segmentation to end-to-end networks to another that eschewed a reconstruction algorithm altogether. Four teams produced strong submissions, with the winner having a weighted Dice Similarity Coefficient of 0.910 ± 0.021 across knee bones and cartilage. Interestingly, there was no correlation between reconstruction and segmentation metrics. Further analysis showed the top four submissions were suitable for downstream biomarker analysis, largely preserving cartilage thicknesses and key bone shape features with respect to ground truth. K2S thus showed the value in considering reconstruction and image analysis as end-to-end tasks, as this leaves room for optimization while more realistically reflecting the long-term use case of tools being developed by the MR community.

Indexed as

compressed sensingdeep learningimage reconstructionmagnetic resonance imagingmulti-task learningmusculoskeletalsegmentation

Identifiers

PMID36829761
PMCPMC9952400

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.