Evidence map›Paper›PMID 36829719›Full record

ArticleBioengineering (Basel, Switzerland)2023

Mechanical Characterization of Human Fascia Lata: Uniaxial Tensile Tests from Fresh-Frozen Cadaver Samples and Constitutive Modelling.

Lorenza Bonaldi, Alice Berardo, Carmelo Pirri, Carla Stecco, Emanuele Luigi Carniel, Chiara Giulia Fontanella

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lorenza BonaldiDepartment of Civil, Environmental and Architectural Engineering, University of Padova, 35131 Padova, Italy.
Alice BerardoDepartment of Civil, Environmental and Architectural Engineering, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-2346-0507
Carmelo PirriDepartment of Neuroscience, Institute of Human Anatomy, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-0119-6549
Carla SteccoCentre for Mechanics of Biological Materials, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-8767-4555
Emanuele Luigi CarnielCentre for Mechanics of Biological Materials, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-1195-2096
Chiara Giulia FontanellaCentre for Mechanics of Biological Materials, University of Padova, 35131 Padova, Italy.ORCID 0000-0003-3844-9842
University of Padua · IT

Funding

Ministry of Education, Universities and Research FISR2019_03221
6 · The paper itself

Abstract

Human Fascia Lata (FL) is a connective tissue with a multilayered organization also known as aponeurotic fascia. FL biomechanics is influenced by its composite structure formed by fibrous layers (usually two) separated by loose connective tissue. In each layer, most of the collagen fibers run parallel in a distinct direction (with an interlayer angle that usually ranges from 75-80°), mirroring the fascia's ability to adapt and withstand specific tensile loads. Although FL is a key structure in several musculoskeletal dysfunctions and in tissue engineering, literature still lacks the evidence that proves tissue anisotropy according to predominant collagen fiber directions. For this purpose, this work aims to analyze the biomechanical properties of ex-vivo FL (collected from fresh-frozen human donors) by performing uniaxial tensile tests in order to highlight any differences with respect to loading directions. The experimental outcomes showed a strong anisotropic behavior in accordance with principal collagen fibers directions, which characterize the composite structure. These findings have been implemented to propose a first constitutive model able to mimic the intra- and interlayer interactions. Both approaches could potentially support surgeons in daily practices (such as graft preparation and placement), engineers during in silico simulation, and physiotherapists during musculoskeletal rehabilitation, to customize a medical intervention based on each specific patient and clinical condition.

Indexed as

biomechanical characterizationconstitutive modellingFascia Latauniaxial tensile test

Identifiers

PMID36829719
PMCPMC9952725
OpenAlexW4319599409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.