Evidence map›Paper›PMID 36829701›Full record

ArticleBioengineering (Basel, Switzerland)2023

Improving Data-Efficiency and Robustness of Medical Imaging Segmentation Using Inpainting-Based Self-Supervised Learning.

Jeffrey Dominic, Nandita Bhaskhar, Arjun D Desai, Andrew Schmidt, Elka Rubin, Beliz Gunel, Garry E Gold, Brian A Hargreaves, Leon Lenchik, Robert Boutin and 1 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jeffrey DominicDepartment of Radiology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-2363-7528
Nandita BhaskharDepartment of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-3624-9169
Arjun D DesaiDepartment of Radiology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-0645-3257
Andrew SchmidtDepartment of Radiology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-3826-6122
Elka RubinDepartment of Radiology, Stanford University, Stanford, CA 94305, USA.
Beliz GunelDepartment of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.
Garry E GoldDepartment of Radiology, Stanford University, Stanford, CA 94305, USA.
Brian A HargreavesDepartment of Radiology, Stanford University, Stanford, CA 94305, USA.
Leon LenchikDepartment of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.
Robert BoutinDepartment of Radiology, Stanford University, Stanford, CA 94305, USA.
Akshay S ChaudhariDepartment of Radiology, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-3667-6796

Funding

Rapid MRI for Evaluation of OsteoarthritisR01EB002524 · NIBIB · STANFORD UNIVERSITY · PI Akshay Chaudhari, Garry E Gold · 2003 to 2026
$10.1M
TR&D Project 3: OpenSim for PredictionP41EB027060 · NIBIB · STANFORD UNIVERSITY · PI Joy P Ku · 2020 to 2026
$9.7M
RADX TECH - CERES NANOSCIENCE INC NANOTRAP PARTICLE MANUFACTURING75N92020C00021 · NHLBI · CERES NANOSCIENCES, LLLP · PI DUNLAP, ROSS · 2021 to 2021
$4.0M
Rapid Low-Cost Quantitative 3D MRI and Gait Assessment of the KneeR01AR077604 · NIAMS · STANFORD UNIVERSITY · PI HARGREAVES, BRIAN ANDREW · 2020 to 2024
$3.2M
Imaging of Joint Response to Physiological Stress with Age, Sex and in OsteoarthritisR01AR079431 · NIAMS · STANFORD UNIVERSITY · PI Feliks Kogan · 2022 to 2026
$2.9M
Advanced MR Imaging of Early OsteoarthritisK24AR062068 · NIAMS · STANFORD UNIVERSITY · PI GOLD, GARRY E · 2012 to 2022
$1.7M
GE Healthcare NANational Science Foundation CCF1563078National Science Foundation CCF1763315National Science Foundation DGE 1656518NHLBI NIH HHS 75N92020C00008NHLBI NIH HHS 75N92020C00021NIAMS NIH HHS K24 AR062068NIAMS NIH HHS R01 AR077604NIAMS NIH HHS R01 AR079431NIBIB NIH HHS P41 EB027060NIBIB NIH HHS R01 EB002524NIH HHS 75N92020C00008NIH HHS 75N92020C00021NIH HHS K24 AR062068NIH HHS P41 EB027060NIH HHS R01 AR077604NIH HHS R01 AR079431NIH HHS R01 EB002524Philips (United States) NAStanford University Precision Health and Integrated Diagnostics Seed GrantUnited States Department of Defense National Science and Engineering Graduate Fellowship (ARO)
6 · The paper itself

Abstract

We systematically evaluate the training methodology and efficacy of two inpainting-based pretext tasks of context prediction and context restoration for medical image segmentation using self-supervised learning (SSL). Multiple versions of self-supervised U-Net models were trained to segment MRI and CT datasets, each using a different combination of design choices and pretext tasks to determine the effect of these design choices on segmentation performance. The optimal design choices were used to train SSL models that were then compared with baseline supervised models for computing clinically-relevant metrics in label-limited scenarios. We observed that SSL pretraining with context restoration using 32 × 32 patches and Poission-disc sampling, transferring only the pretrained encoder weights, and fine-tuning immediately with an initial learning rate of 1 × 10-3 provided the most benefit over supervised learning for MRI and CT tissue segmentation accuracy (

Indexed as

CTdeep learningmachine learningMRIsegmentationself-supervised learning

Identifiers

PMID36829701
PMCPMC9951871

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.