Evidence map›Paper›PMID 36829636›Full record

ArticleBioengineering (Basel, Switzerland)2023

Design of an Automatically Controlled Multi-Axis Stretching Device for Mechanical Evaluations of the Anterior Eye Segment.

Kehao Wang, Ziyan Qiu, Yiping Xie, Shuo Cai, Yang Zhao, Barbara K Pierscionek, Jiangzhen Guo, Yubo Fan

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Kehao WangKey Laboratory for Biomechanics and Mechanobiology of Ministry for Education, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, China.ORCID 0000-0001-5485-7091
Ziyan QiuKey Laboratory for Biomechanics and Mechanobiology of Ministry for Education, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, China.
Yiping XieSchool of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing 100043, China.ORCID 0000-0002-6269-7830
Shuo CaiSchool of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China.
Yang ZhaoKey Laboratory for Biomechanics and Mechanobiology of Ministry for Education, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, China.
Barbara K PierscionekFaculty of Health, Education, Medicine and Social Care, Medical Technology Research Centre, Anglia Ruskin University, Bishops Hall Lane, Chelmsford, CM1 1SQ, UK.ORCID 0000-0002-8661-6353
Jiangzhen GuoKey Laboratory for Biomechanics and Mechanobiology of Ministry for Education, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, China.ORCID 0000-0001-8941-2893
Yubo FanKey Laboratory for Biomechanics and Mechanobiology of Ministry for Education, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, China.
Beihang University · CNAnglia Ruskin University · GBChinese Academy of Sciences · CN

Funding

Higher Education Discipline Innovation Project the 111 Project No: B13003National Natural Science Foundation of China 51905021National Natural Science Foundation of China 82000878
6 · The paper itself

Abstract

The young eye has an accommodative ability involving lens shape changes to focus over different distances. This function gradually decreases with age, resulting in presbyopia. Greater insights into the mechanical properties of anterior eye structures can improve understanding of the causes of presbyopia. The present study aims to develop a multi-axis stretching device for evaluating the mechanical properties of the intact eye lens. A stretching device integrating the mechanical stretcher, motor, torque sensor and data transmission mechanism was designed and developed by 3D printing. The mechanical stretcher can convert rotation into radial movement, both at constant speeds, according to the spiral of Archimedes. The loading unit equipped with eight jaws can hold the eye sample tightly. The developed device was validated with a spring of known constant and was further tested with anterior porcine eye segments. The validation experiment using the spring resulted in stiffness values close to the theoretical spring constant. Findings from measurements with porcine eye samples indicated that the measured forces are within the ranges reported in the literature. The developed multi-axis stretching device has good repeatability during experiments with similar settings and can be reliably used for mechanical evaluations of the intact eye lens.

Indexed as

biomechanicscataractlensmulti-axis loadingpresbyopiastretching device

Identifiers

PMID36829636
PMCPMC9952546
OpenAlexW4317616229

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.