Evidence map›Paper›PMID 36829618›Full record

ReviewBioengineering (Basel, Switzerland)2023

Vascularized Tissue Organoids.

Hannah A Strobel, Sarah M Moss, James B Hoying

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
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  12. Bioengineering vascularization.Development (Cambridge, England) · 2024
    Review
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  15. Application of tumor organoids simulating the tumor microenvironment in basic and clinical research of tumor immunotherapy.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
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  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hannah A StrobelAdvanced Solutions Life Sciences, Manchester, NH 03101, USA.
Sarah M MossAdvanced Solutions Life Sciences, Manchester, NH 03101, USA.
James B HoyingAdvanced Solutions Life Sciences, Manchester, NH 03101, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue organoids hold enormous potential as tools for a variety of applications, including disease modeling and drug screening. To effectively mimic the native tissue environment, it is critical to integrate a microvasculature with the parenchyma and stroma. In addition to providing a means to physiologically perfuse the organoids, the microvasculature also contributes to the cellular dynamics of the tissue model via the cells of the perivascular niche, thereby further modulating tissue function. In this review, we discuss current and developing strategies for vascularizing organoids, consider tissue-specific vascularization approaches, discuss the importance of perfusion, and provide perspectives on the state of the field.

Indexed as

endothelialextracellular matrixmicrovesselorganoidperfusionspheroidstem cellvascularizationvascular networkvessel

Identifiers

PMID36829618
PMCPMC9951914
OpenAlexW4317207030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.