ArticleBiology2023
Quantitative Load Dependency Analysis of Local Trabecular Bone Microstructure to Understand the Spatial Characteristics in the Synthetic Proximal Femur.
Article in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Regional and depth-dependent associations between subchondral bone and cartilage in hip osteoarthritis: a preliminary [Skeletal radiology · 2026Article
- Structural Behavior Analysis of a Bone-Scaffold System According to the Elastic Modulus of Bone Cement and Pore Size in the Proximal Femur.Journal of functional biomaterials · 2026Article
- Measurement of the principal compressive trabeculae in the midcoronal plane of proximal femur and its significance in lag screw fixation.Journal of orthopaedic surgery and research · 2026Article
- Strategies for the Patient-Specific Implant Angle of Bone Scaffolds Using Optimization.Tissue engineering and regenerative medicine · 2025Article
- Functional morphology of trabecular system in human proximal femur: a perspective from P45 sectional plastination and 3D reconstruction finite element analysis.Journal of orthopaedic surgery and research · 2025Article
- Quantitative Analysis of Primary Compressive Trabeculae Distribution in the Proximal Femur of the Elderly.Orthopaedic surgery · 2024Article
- Finite element study on post-screw removal stress in toy poodle radius with different plate designs and screw arrangements.Open veterinary journal · 2024Article
- Mapping the Spatial Evolution of Proximal Femur Osteoporosis: A Retrospective Cross-Sectional Study Based on CT Scans.International journal of general medicine · 2024Article
- An Analysis of Trabecular Bone Structure Based on Principal Stress Trajectory.Bioengineering (Basel, Switzerland) · 2023Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Analysis of the dependency of the trabecular structure on loading conditions is essential for understanding and predicting bone structure formation. Although previous studies have investigated the relationship between loads and structural adaptations, there is a need for an in-depth analysis of this relationship based on the bone region and load specifics. In this study, the load dependency of the trabecular bone microstructure for twelve regions of interest (ROIs) in the synthetic proximal femur was quantitatively analyzed to understand the spatial characteristics under seven different loading conditions. To investigate the load dependency, a quantitative measure, called the load dependency score (LDS), was established based on the statistics of the strain energy density (SED) distribution. The results showed that for the global model and epiphysis ROIs, bone microstructures relied on the multiple-loading condition, whereas the structures in the metaphysis depended on single or double loads. These results demonstrate that a given ROI is predominantly dependent on a particular loading condition. The results confirm that the dependency analysis of the load effects for ROIs should be performed both qualitatively and quantitatively.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.