Evidence map›Paper›PMID 36829246›Full record

ReviewMilitary Medical Research2023

Bioengineered materials with selective antimicrobial toxicity in biomedicine.

Pooyan Makvandi, Hao Song, Cynthia K Y Yiu, Rossella Sartorius, Ehsan Nazarzadeh Zare, Navid Rabiee, Wei-Xi Wu, Ana Cláudia Paiva-Santos, Xiang-Dong Wang, Cheng-Zhong Yu and 1 more

Erratum issuedOpen access · diamondAbstract readReview
In one paragraph

Review in Military Medical Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Ferroptosis-mediated intestinal decolonization ofFrontiers in microbiology · 2026
    Article
  4. Review
  5. Review
  6. Evaluation of the Antibacterial Activity ofCurrent pharmaceutical design · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 7 countries.

Pooyan MakvandiThe Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, 324000, Zhejiang, China. pooyanmakvandi@gmail.com.
Hao SongAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia.
Cynthia K Y YiuPaediatric Dentistry and Orthodontics, Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, Hong Kong SAR, China.
Rossella SartoriusInstitute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), 80131, Naples, Italy.
Ehsan Nazarzadeh ZareSchool of Chemistry, Damghan University, Damghan, 36716-45667, Iran. ehsan.nazarzadehzare@gmail.com.
Navid RabieeSchool of Engineering, Macquarie University, Sydney, NSW, 2109, Australia.
Wei-Xi WuAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia.
Ana Cláudia Paiva-SantosDepartment of Pharmaceutical Technology, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, 3000-548, Coimbra, Portugal.
Xiang-Dong WangDepartment of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Fudan University Shanghai Medical College, Shanghai, 200032, China.
Cheng-Zhong YuAustralian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia.
Franklin R TayThe Graduate School, Augusta University, Augusta, GA, 30912, USA. ftay@augusta.edu.ORCID http://orcid.org/0000-0003-3769-0626
The University of Queensland · AUDamghan University · IRItalian Institute of Technology · ITMurdoch University · AUNational Research Council · ITPrince Philip Dental Hospital · CNRede de Química e Tecnologia · PTShanghai Medical College of Fudan University · CNThe Graduate Center, CUNY · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi and bacteria afflict humans with innumerous pathogen-related infections and ailments. Most of the commonly employed microbicidal agents target commensal and pathogenic microorganisms without discrimination. To distinguish and fight the pathogenic species out of the microflora, novel antimicrobials have been developed that selectively target specific bacteria and fungi. The cell wall features and antimicrobial mechanisms that these microorganisms involved in are highlighted in the present review. This is followed by reviewing the design of antimicrobials that selectively combat a specific community of microbes including Gram-positive and Gram-negative bacterial strains as well as fungi. Finally, recent advances in the antimicrobial immunomodulation strategy that enables treating microorganism infections with high specificity are reviewed. These basic tenets will enable the avid reader to design novel approaches and compounds for antibacterial and antifungal applications.

Indexed as

Anti-Infective AgentsAnti-Bacterial AgentsBacteriaHumansAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial nanotechnologyImmumodualtionSelective toxicitySmart nanomaterialsTargeting microorganism

Identifiers

PMID36829246
PMCPMC9951506
OpenAlexW4321786367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.