Evidence map›Paper›PMID 36829190›Full record

ArticleFrontiers in zoology2023

Concerted phenotypic flexibility of avian erythrocyte size and number in response to dietary anthocyanin supplementation.

Maciej Dzialo, Amadeusz Bryła, Kristen J DeMoranville, Katherine M Carbeck, Olivia Fatica, Lisa Trost, Barbara Pierce, Edyta T Sadowska, Scott R McWilliams, Ulf Bauchinger

Abstract read
In one paragraph

Article in Frontiers in zoology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maciej DzialoFaculty of Biology, Institute of Environmental Sciences, Jagiellonian University, 30-387, Kraków, Poland. maciej.dzialo@doctoral.uj.edu.pl.ORCID http://orcid.org/0000-0002-3632-8572
Amadeusz BryłaFaculty of Biology, Institute of Environmental Sciences, Jagiellonian University, 30-387, Kraków, Poland.
Kristen J DeMoranvilleDepartment of Natural Resources Science, University of Rhode Island, Kingston, RI, 02881, USA.
Katherine M CarbeckDepartment of Forest and Conservation Sciences, University of British Columbia, Vancouver, BC, V6T1Z4, Canada.
Olivia FaticaDepartment of Biology, Sacred Heart University, Fairfield, CT, 06825, USA.
Lisa TrostDepartment for Behavioural Neurobiology, Max Planck Institute for Ornithology, 82319, Seewiesen, Germany.
Barbara PierceDepartment of Biology, Sacred Heart University, Fairfield, CT, 06825, USA.
Edyta T SadowskaFaculty of Biology, Institute of Environmental Sciences, Jagiellonian University, 30-387, Kraków, Poland.
Scott R McWilliamsDepartment of Natural Resources Science, University of Rhode Island, Kingston, RI, 02881, USA.
Ulf BauchingerFaculty of Biology, Institute of Environmental Sciences, Jagiellonian University, 30-387, Kraków, Poland.

Funding

National Science Foundation, Poland UMO-2015/19/B/NZ8/01394National Science Foundation, US IOS-1354187
6 · The paper itself

Abstract

backgroundEndurance flight impose substantial oxidative costs on the avian oxygen delivery system. In particular, the accumulation of irreversible damage in red blood cells can reduce the capacity of blood to transport oxygen and limit aerobic performance. Many songbirds consume large amounts of anthocyanin-rich fruit, which is hypothesized to reduce oxidative costs, enhance post-flight regeneration, and enable greater aerobic capacity. While their antioxidant benefits appear most straightforward, the effects of anthocyanins on blood composition remain so far unknown. We fed thirty hand-raised European starlings (Sturnus vulgaris) two semisynthetic diets (with or without anthocyanin supplement) and manipulated the extent of flight activity in a wind tunnel (daily flying or non-flying for over two weeks) to test for their interactive effects on functionally important haematological variables.

resultsSupplemented birds had on average 15% more and 4% smaller red blood cells compared to non-supplemented individuals and these diet effects were independent of flight manipulation. Haemoglobin content was 7% higher in non-supplemented flying birds compared to non-flying birds, while similar haemoglobin content was observed among supplemented birds that were flown or not. Neither diet nor flight activity influenced haematocrit.

conclusionThe concerted adjustments suggest that supplementation generally improved antioxidant protection in blood, which could prevent the excess removal of cells from the bloodstream and may have several implications on the oxygen delivery system, including improved gas exchange and blood flow. The flexible haematological response to dietary anthocyanins may also suggest that free-ranging species preferentially consume anthocyanin-rich fruits for their natural blood doping, oxygen delivery-enhancement effects.

Indexed as

Anthocyanin supplementationAntioxidant dietCell numberCell sizeErythrocytesPhenotypic flexibilityRed blood cells

Identifiers

PMID36829190
PMCPMC9951440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.