Evidence map›Paper›PMID 36829088›Full record

Observational studyActa neurologica Belgica2023

Simple febrile seizures: new cut off for the duration of the crises.

Raffaele Falsaperla, Silvia Marino, Giovanna Vitaliti, Anna Bonadies, Simona Domenica Marino, Piero Pavone, Catia Romano, Fabio Savoia, Camilla Calì, Martino Ruggieri and 2 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Acta neurologica Belgica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Raffaele FalsaperlaPediatric and Pediatric Emergency Department, University Hospital "Rodolico - San Marco", PO "San Marco", Via A. Ciampi, 2, 95100, Catania, Italy.
Silvia MarinoPediatric and Pediatric Emergency Department, University Hospital "Rodolico - San Marco", PO "San Marco", Via A. Ciampi, 2, 95100, Catania, Italy. silvia_marino86@hotmail.it.ORCID http://orcid.org/0000-0001-6598-9903
Giovanna VitalitiPediatric and Pediatric Emergency Department, University Hospital "Rodolico - San Marco", PO "San Marco", Via A. Ciampi, 2, 95100, Catania, Italy.
Anna BonadiesDepartment of Pediatric, AORN Santobono Pausilipon, Naples, Italy.
Simona Domenica MarinoPediatric and Pediatric Emergency Department, University Hospital "Rodolico - San Marco", PO "San Marco", Via A. Ciampi, 2, 95100, Catania, Italy.
Piero PavoneDepartment of Clinical and Experimental Medicine, Section of Pediatrics and Child Neuropsychiatry, University Hospital "Rodolico - San Marco", PO "Rodolico", Catania, Italy.
Catia RomanoPediatric and Pediatric Emergency Department, University Hospital "Rodolico - San Marco", PO "San Marco", Via A. Ciampi, 2, 95100, Catania, Italy.
Fabio SavoiaEvaluative Epidemiology-Childhood Cancer Registry of Campania, AORN "Santobono-Pausilipon Children's Hospital", Naples, Italy.
Camilla CalìEvaluative Epidemiology-Childhood Cancer Registry of Campania, AORN "Santobono-Pausilipon Children's Hospital", Naples, Italy.
Martino RuggieriUnit of Rare Diseases of the Nervous System in Childhood, Department of Clinical and Experimental Medicine, Section of Pediatrics and Child Neuropsychiatry, University of Catania, Catania, Italy.
Riccardo LubranoDepartment of Paediatrics, University of Rome "La Sapienza", Rome, Italy.
Vincenzo TipoDepartment of Pediatric, AORN Santobono Pausilipon, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOur study aimed to identify a new cut-off for febrile seizure (FS) with a good prognosis, thereby replacing the 15 min described in the standard definition of simple febrile seizure (SFS).

methodsOur study was a retrospective observational study (from January 2018 to December 2018) on children admitted to the Pediatric emergency room of the Santobono-Pausilipon Hospital, Naples, Italy, Pediatric Unit of Latina, Rome, Italy, and Policlinico-Vittorio-Emanuele University Hospital, Catania, Italy, for fever, which developed SFS during the hospitalization. All included patients had their seizures classified as SFS according to the international criteria for epilepsy. We assumed a duration cut-off, and we analyzed the EEG results, neurological follow-up at 12 months, and the recurrence of the febrile seizures the following year. Then, with another calculation, we identify an optimal cut-off of 6 min. Finally, we divided the population into two groups: children with seizures having a duration greater than or less than 6 min.

resultsWe found that the population with FS with a duration greater than 6 min presented EEG alteration at follow-up visits, neurological disorders, and a recurrence of FS during the following year.

conclusionsWe suggest to introduce a new cut-off for the duration of FS that better represents the benign nature of a simple febrile event.

Indexed as

EpilepsySeizures, FebrileChildFeverHospitals, UniversityHumansInfantRetrospective StudiesClassificationPediatricsRetrospective studySeizuresSimple febrile seizures

Identifiers

PMID36829088

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.