Evidence map›Paper›PMID 36828578›Full record

ArticleRespiratory care2023

Therapeutic Response to Single-Inhaler Triple Therapies in Moderate-to-Severe COPD.

Kengo Ohtsuka, Naoko Harada, Atsuo Horiuchi, Shintaro Umemoto, Ryo Kurabatashi, Akie Yui, Hiroyuki Yamamura, Yoko Shinka, Naoki Miyao

Open access · greenAbstract read
In one paragraph

Article in Respiratory care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kengo OhtsukaDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan.
Naoko HaradaDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan.
Atsuo HoriuchiDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan.
Shintaro UmemotoDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan.
Ryo KurabatashiDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan.
Akie YuiDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan.
Hiroyuki YamamuraDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan.
Yoko ShinkaDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan.
Naoki MiyaoDepartment of Internal Medicine, Nippon Koukan Hospital, Kawasaki, Kanagawa, Japan. naoki-miyao@koukankai.or.jp.
Nippon Koei (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOPD is characterized by progressive and irreversible air flow limitations. Single-inhaler therapies (SITTs) incorporating an inhaled corticosteroid, a long-acting muscarinic antagonist, and a long-acting β

methodsWe assessed the pulmonary function test results of subjects with COPD before and one month after using F/U/V and B/G/F as SITT. Subjects with a difference of 100 mL or more in the FEV

resultsF/U/V and B/G/F significantly improved the inspiratory capacity (IC), %IC, FVC, and %FEV

conclusionsOur results showed that SITT significantly improved the IC, %IC, FVC, and %FEV

Indexed as

Bronchodilator AgentsPulmonary Disease, Chronic ObstructiveAdministration, InhalationBenzyl AlcoholsBudesonide, Formoterol Fumarate Drug CombinationChlorobenzenesDouble-Blind MethodDyspneaFluticasoneFormoterol FumarateHumansNebulizers and VaporizersBenzyl AlcoholsBronchodilator AgentsBudesonide, Formoterol Fumarate Drug CombinationChlorobenzenesFluticasoneFormoterol Fumaratevilanterolbudesonide/glycopyrrolate/formoterolCOPDfluticasone-furoate/umeclidinium/vilanterolinspiratory capacitymodified Medical Research Council

Identifiers

PMID36828578
PMCPMC10027151
OpenAlexW4321791622

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.