ArticleToxins2023
Children and Snakebite: Snake Venom Effects on Adult and Paediatric Plasma.
Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Effects of Cape Cobra (Toxins · 2026Article
- Paediatric Snakebite Toxicity up to Compartment Syndrome: A Ten-Year Retrospective Study in Iasi, Romania.Toxins · 2026Observational
- Predictors of In-Hospital Mortality Among Paediatric Snakebite Patients in Northeastern Nigeria: A Survival Analysis Study.Wellcome open research · 2026Article
- Analyzing first aid in textbooks used by non-medical and paramedical students in Nepal: A need of further attention for snakebite management!PLoS neglected tropical diseases · 2025Article
- Epidemiology of paediatric snakebites in Northeastern Nigeria: a retrospective single-center study.BMC pediatrics · 2025Article
- Preventive practices and parental attitudes towards snakebites in children in snakebite hotspots of rural Sri Lanka.BMJ paediatrics open · 2025Article
- Caught between fear and tradition: parental knowledge, beliefs and emergency responses to paediatric snakebites in rural Sri Lanka.BMJ paediatrics open · 2025Article
- Article
- Article
- Tiny but Mighty:Toxins · 2024Article
- Factors associated with mortality after snakebite envenoming in children: a scoping review.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2023Article
- Analysis of News Media-Reported Snakebite Envenoming in Nepal during 2010-2022.PLoS neglected tropical diseases · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Snakebite is a globally neglected tropical disease, with coagulation disturbances being the primary pathology of many deadly snake venoms. Age-related differences in human plasma have been abundantly reported, yet the effect that these differences pose regarding snakebite is largely unknown. We tested for differences in coagulotoxic effects (via clotting time) of multiple snake venoms upon healthy human adult (18+) and paediatric (median 3.3 years old) plasma in vivo and compared these effects to the time it takes the plasmas to clot without the addition of venom (the spontaneous clotting time). We tested venoms from 15 medically significant snake species (from 13 genera) from around the world with various mechanisms of coagulotoxic actions, across the three broad categories of procoagulant, pseudo-procoagulant, and anticoagulant, to identify any differences between the two plasmas in their relative pathophysiological vulnerability to snakebite. One procoagulant venom (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.