Evidence map›Paper›PMID 36828462›Full record

ArticleToxins2023

Multi-Mycotoxin Method Development Using Ultra-High Liquid Chromatography with Orbitrap High-Resolution Mass Spectrometry Detection in Breakfast Cereals from the Campania Region, Italy.

Alfonso Narváez, Luana Izzo, Luigi Castaldo, Sonia Lombardi, Yelko Rodríguez-Carrasco, Alberto Ritieni

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Alfonso NarváezDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-4328-2330
Luana IzzoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-8365-9032
Luigi CastaldoDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0001-6883-9396
Sonia LombardiDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-4447-0798
Yelko Rodríguez-CarrascoLaboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, Burjassot, 46100 Valencia, Spain.ORCID 0000-0002-6421-218X
Alberto RitieniDepartment of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0003-0314-8839
University of Naples Federico II · ITFederico II University Hospital · ITUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breakfast cereals have been reported as one of the most susceptible cereal-based products to mycotoxin contamination. These products pose an even more concerning risk to human health since they are marketed as a ready-to-eat product and one of its main population targets is children. Therefore, the main goal of the present study was to conduct a monitoring study of multiple mycotoxins contained in breakfast cereals samples marketed in Italy through ultra-high performance liquid chromatography coupled to high-resolution Q-Orbitrap tandem mass spectrometry. An acetonitrile-based methodology was validated for quantifying 24 mycotoxins in breakfast cereals. The results showed that 93% of the samples contained at least one mycotoxin. Beauvericin was the most prevalent toxin (86% of samples; mean concentration: 30.66 µg/kg), although the main enniatins, zearalenone-derived forms and fumonisins B1 and B2 were also detected. Co-occurrence was observed in 73% of the positive samples with up to five mycotoxins simultaneously occurring, mainly due to the combination of beauvericin and enniatins. These results provided more evidence about the high impact of non-regulated mycotoxins, such as the emerging

Indexed as

MycotoxinsZearalenoneBreakfastChildChromatography, High Pressure LiquidChromatography, LiquidEdible GrainFood ContaminationHumansItalyTandem Mass SpectrometryMycotoxinsZearalenonebreakfast cerealsfood safetyhigh-resolution mass spectrometrymycotoxins

Identifiers

PMID36828462
PMCPMC9962421
OpenAlexW4320494273

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.