Evidence map›Paper›PMID 36828408›Full record

ReviewToxins2023

Antifungal and Antibacterial Activities of Isolated Marine Compounds.

Amin Mahmood Thawabteh, Zain Swaileh, Marwa Ammar, Weam Jaghama, Mai Yousef, Rafik Karaman, Sabino A Bufo, Laura Scrano

Abstract readReview
In one paragraph

Review in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Enhancement ofFood chemistry: X · 2025
    Article
  9. Review
  10. Article
  11. Identification and Antimicrobial Potential of Marine Sponges (International journal of microbiology · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Skin Pigmentation Types, Causes and Treatment-A Review.Molecules (Basel, Switzerland) · 2023
    Review
  19. MarineMarine drugs · 2023
    Review
  20. Modern Trends in Natural Antibiotic Discovery.Life (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amin Mahmood ThawabtehGeneral Safety Section, General Services Department, Birzeit University, Ramallah 00972, Palestine.ORCID 0000-0002-0672-9439
Zain SwailehFaculty of Pharmacy, Nursing and Health Professions, Birzeit University, Ramallah 00972, Palestine.ORCID 0000-0002-8428-5634
Marwa AmmarFaculty of Pharmacy, Nursing and Health Professions, Birzeit University, Ramallah 00972, Palestine.ORCID 0000-0001-8991-7998
Weam JaghamaFaculty of Pharmacy, Nursing and Health Professions, Birzeit University, Ramallah 00972, Palestine.
Mai YousefFaculty of Pharmacy, Nursing and Health Professions, Birzeit University, Ramallah 00972, Palestine.
Rafik KaramanPharmaceutical Sciences Department, Faculty of Pharmacy, Al-Quds University, Jerusalem 20002, Palestine.ORCID 0000-0001-5526-4490
Sabino A BufoDepartment of Sciences, University of Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0002-0857-2367
Laura ScranoDepartment of European and Mediterranean Cultures, University of Basilicata, Via Lanera 20, 75100 Matera, Italy.ORCID 0000-0002-3716-2666

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To combat the ineffectiveness of currently available pharmaceutical medications, caused by the emergence of increasingly resistant bacterial and fungal strains, novel antibacterial and antifungal medications are urgently needed. Novel natural compounds with antimicrobial activities can be obtained by exploring underexplored habitats such as the world's oceans. The oceans represent the largest ecosystem on earth, with a high diversity of organisms. Oceans have received some attention in the past few years, and promising compounds with antimicrobial activities were isolated from marine organisms such as bacteria, fungi, algae, sea cucumbers, sea sponges, etc. This review covers 56 antifungal and 40 antibacterial compounds from marine organisms. These compounds are categorized according to their chemical structure groups, including polyketides, alkaloids, ribosomal peptides, and terpenes, and their organismal origin. The review provides the minimum inhibitory concentration MIC values and the bacterial/fungal strains against which these chemical compounds show activity. This study shows strong potential for witnessing the development of new novel antimicrobial drugs from these natural compounds isolated and evaluated for their antimicrobial activities.

Indexed as

Antifungal AgentsAnti-Infective AgentsAnti-Bacterial AgentsAquatic OrganismsBacteriaEcosystemFungiAnti-Bacterial AgentsAntifungal AgentsAnti-Infective Agentsantibacterial activityantifungal activitybacterial resistancemarine compoundsminimum inhibitory concentration (MIC)

Identifiers

PMID36828408
PMCPMC9966175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.