Evidence map›Paper›PMID 36828379›Full record

ArticleTomography (Ann Arbor, Mich.)2023

T1-Weighted Contrast Enhancement, Apparent Diffusion Coefficient, and Cerebral-Blood-Volume Changes after Glioblastoma Resection: MRI within 48 Hours vs. beyond 48 Hours.

Davide Negroni, Romina Bono, Eleonora Soligo, Vittorio Longo, Christian Cossandi, Alessandro Carriero, Alessandro Stecco

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tomography (Ann Arbor, Mich.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Davide NegroniRadiology Department, Maggiore della Carità Hospital of Novara, 28100 Novara, Italy.
Romina BonoRadiology Department, Maggiore della Carità Hospital of Novara, 28100 Novara, Italy.
Eleonora SoligoRadiology Department, San Andrea Hospital of Vercelli, 13100 Vercelli, Italy.
Vittorio LongoRadiology Department, Maggiore della Carità Hospital of Novara, 28100 Novara, Italy.
Christian CossandiNeurosurgery Department, Maggiore della Carità Hospital of Novara, 28100 Novara, Italy.
Alessandro CarrieroRadiology Department, Maggiore della Carità Hospital of Novara, 28100 Novara, Italy.
Alessandro SteccoRadiology Department, Maggiore della Carità Hospital of Novara, 28100 Novara, Italy.ORCID 0000-0002-0712-7595
Azienda Ospedaliera Ospedale Maggiore · ITCTO Andrea Alesini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the study is to identify the advantages, if any, of post-operative MRIs performed at 48 h compared to MRIs performed after 48 h in glioblastoma surgery. MATERIALS AND

methodsTo assess the presence of a residual tumor, the T1-weighted Contrast Enhancement (CE), Apparent Diffusion Coefficient (ADC), and Cerebral Blood Volume (rCBV) in the proximity of the surgical cavity were considered. The rCBV ratio was calculated by comparing the rCBV with the contralateral normal white matter. After the blind image examinations by the two radiologists, the patients were divided into two groups according to time window after surgery: ≤48 h (group 1) and >48 h (group 2).

resultsA total of 145 patients were enrolled; at the 6-month follow-up MRI, disease recurrence was 89.9% (125/139), with a mean patient survival of 8.5 months (SD 7.8). The mean ADC and rCBV ratio values presented statistical differences between the two groups (

conclusionThe study showed differences in CE, rCBV, and ADC values between the groups of patients undergoing MRIs before and after 48 h. An MRI performed within 48 h may increase the ability of detecting GBM by the perfusion technique with the calculation of the rCBV ratio.

Indexed as

Brain NeoplasmsGlioblastomaCerebral Blood VolumeDiffusion Magnetic Resonance ImagingHumansMagnetic Resonance Imagingapparent diffusion coefficientcerebral blood volumediffusiondynamic susceptibility contrastglioblastomaMRIperfusionsurgical marginsT1 post-contrasttime window

Identifiers

PMID36828379
PMCPMC9967426
OpenAlexW4319003248

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.