Evidence map›Paper›PMID 36828378›Full record

ReviewTomography (Ann Arbor, Mich.)2023

Advances in the Assessment of Coronary Artery Disease Activity with PET/CT and CTA.

Jacek Kwiecinski, Rafal Wolny, Alicja Chwala, Piotr Slomka

Open access · goldAbstract readReview
In one paragraph

Review in Tomography (Ann Arbor, Mich.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  13. Medical Radiology: Current Progress.Diagnostics (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Jacek KwiecinskiDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Rafal WolnyDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, 04-628 Warsaw, Poland.ORCID 0000-0001-9661-7563
Alicja ChwalaDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, 04-628 Warsaw, Poland.
Piotr SlomkaDepartment of Medicine (Artificial Intelligence in Medicine), Imaging, and Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Institute of Cardiology · PLCedars-Sinai Medical Center · US

Funding

Integrated analysis of coronary anatomy and biology with 18F-fluoride PET and CT angiographyR01HL135557 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI SLOMKA, PIOTR J · 2017 to 2020
$3.0M
NIH HHS R01HL135557
6 · The paper itself

Abstract

Non-invasive testing plays a pivotal role in the diagnosis, assessment of progression, response to therapy, and risk stratification of coronary artery disease. Although anatomical plaque imaging by computed tomography angiography (CTA) and ischemia detection with myocardial perfusion imaging studies are current standards of care, there is a growing body of evidence that imaging of the processes which drive atherosclerotic plaque progression and rupture has the potential to further enhance risk stratification. In particular, non-invasive imaging of coronary plaque inflammation and active calcification has shown promise in this regard. Positron emission tomography (PET) with newly-adopted radiotracers provides unique insights into atheroma activity acting as a powerful independent predictor of myocardial infarctions. Similarly, by providing a quantitative measure of coronary inflammation, the pericoronary adipose tissue density (PCAT) derived from standard coronary CTA enhances cardiac risk prediction and allows re-stratification over and above current state-of-the-art assessments. In this review, we shall discuss the recent advances in the non-invasive methods of assessment of disease activity by PET and CTA, highlighting how these methods could improve risk stratification and ultimately benefit patients with coronary artery disease.

Indexed as

Coronary Artery DiseasePlaque, AtheroscleroticComputed Tomography AngiographyCoronary AngiographyHumansInflammationPositron-Emission TomographyPositron Emission Tomography Computed Tomography18F-sodium fluoridecoronary artery diseasecoronary computed tomography angiographycoronary positron emission tomographypericoronary adipose tissue attenuation

Identifiers

PMID36828378
PMCPMC9962109
OpenAlexW4319003569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.