Evidence map›Paper›PMID 36827712›Full record

ArticleBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2023

The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro.

Rocky Lowenthal, Megan Taylor, Jennifer A Gidden, Billie Heflin, Jackson O Lay, Nathan Avaritt, Alan J Tackett, Alicja Urbaniak

Open access · goldAbstract read
In one paragraph

Article in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. Review
  6. Biopolymers of Polycaprolactone Loaded with Caffeic Acid andInternational journal of molecular sciences · 2025
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  7. Enhanced Anti-Cancer Potential: Investigating the Combined Effects withInternational journal of molecular sciences · 2025
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  8. A Chromosome-Scale Genome ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Review
  11. Review
  12. Article
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  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Rocky LowenthalDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States.
Megan TaylorDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States.
Jennifer A GiddenArkansas Statewide MS Facility, University of Arkansas, Fayetteville 72701, AR, United States.
Billie HeflinDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States.
Jackson O LayArkansas Statewide MS Facility, University of Arkansas, Fayetteville 72701, AR, United States; Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville 72701, AR, United States.
Nathan AvarittDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States.
Alan J TackettDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States. Electronic address: AJTackett@uams.edu.
Alicja UrbaniakDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States. Electronic address: aurbaniak@uams.edu.
University of Arkansas for Medical Sciences · USUniversity of Arkansas at Fayetteville · US

Funding

Translational Regulation in Normal Erythropoiesis and Diamond Blackfan AnemiaP20GM121293 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI Alan Tackett, Sean D. Taverna · 2017 to 2026
$27.6M
Supplement for Google cloud build-outR24GM137786 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Alan Tackett · 2020 to 2026
$15.4M
Identification of Druggable Targets to Complement Melanoma TherapyR01CA236209 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI TACKETT, ALAN · 2019 to 2023
$1.7M
NCI NIH HHS R01 CA236209NIGMS NIH HHS P20 GM121293NIGMS NIH HHS R24 GM137786
6 · The paper itself

Abstract

Melanoma is one of the most aggressive forms of skin cancer and is characterized by high metastatic potential. Despite improvements in early diagnosis and treatment, the mortality rate among metastatic melanoma patients continues to represent a significant clinical challenge. Therefore, it is imperative that we search for new forms of treatment. Trametes versicolor is a mushroom commonly used in Chinese traditional medicine due to its numerous beneficial properties. In the present work, we demonstrate T. versicolor fruiting body and mycelium ethanol extracts exhibit potent cytotoxic activity towards A375 (IC

Indexed as

Antineoplastic AgentsPolyporaceaeHumansMyceliumTrametesAntineoplastic AgentsCoriolus versicolorMelanomaMushroomTrametes versicolorTurkey tail

Identifiers

PMID36827712
PMCPMC10147383
OpenAlexW4321523262

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.