Trial reportJournal of speech, language, and hearing research : JSLHR2023
Predicting Outcomes of Language Rehabilitation: Prognostic Factors for Immediate and Long-Term Outcomes After Aphasia Therapy.
Trial report in Journal of speech, language, and hearing research : JSLHR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 38 citations in OpenAlex.
- Rehabilitation of post-stroke aphasia by a single protocol targeting phonological, lexical, and semantic deficits with speech output tasks: a randomized controlled trial.European journal of physical and rehabilitation medicine · 2025Trial
- Critical-Network Lesion-Symptom Mapping.Human brain mapping · 2026Article
- Narrative Discourse Predictors of Response to Naming Intervention in Aphasia.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Characterizing Verb Argument Structure in Aphasia Using Dependency Parsers.Journal of speech, language, and hearing research : JSLHR · 2026Article
- Rethinking anomia across the frontotemporal dementia spectrum: marker of language dysfunction or global cognitive decline?medRxiv : the preprint server for health sciences · 2026Article
- Aphasia severity mediates the relationship between attention and sentence comprehension.Aphasiology · 2026Article
- How object naming dissociates from repetition and comprehension impairments when post stroke aphasia is less severe.Scientific reports · 2026Article
- Digital Twin Model of Treatment Outcomes in Post-Stroke Aphasia.medRxiv : the preprint server for health sciences · 2026Article
- Cortical hierarchy and aphasia severity: the sensorimotor-association gradient modulates lesion effects within language-specific networks.Communications biology · 2026Article
- The Effect of Age on Post-Stroke Language Outcomes.Journal of aging research · 2026Article
- The association between nonverbal fluency and anomia treatment outcomes in people with post-stroke aphasia.Frontiers in human neuroscience · 2026Article
- PICTURE-IT: a pilot randomized cross-over trial encouraging right-hemisphere engagement for the treatment of aphasia via telemedicine.Aphasiology · 2025Article
- Mapping of critical prosodic and phonetic networks in post-stroke apraxia of speech.bioRxiv : the preprint server for biology · 2025Article
- Naming practice effects and inconsistencies relate to treatment outcome in people with aphasia.Neuropsychologia · 2025Article
- Aphasia severity mediates the relationship between attention and sentence comprehension.bioRxiv : the preprint server for biology · 2025Article
- Article
- Multifactorial interplay on language recovery following left-hemispheric stroke: A retrospective study.Journal of neuropsychology · 2025Article
- An Introduction to Machine Learning for Speech-Language Pathologists: Concepts, Terminology, and Emerging Applications.Perspectives of the ASHA special interest groups · 2025Article
- Neural Predictors for the Generalization of Semantic and Phonological Treatment to Discourse Performance in Chronic Post-Stroke Aphasia.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Partial least squares multimodal analysis of brain network correlates of language deficits in aphasia.Brain communications · 2025Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAphasia therapy is an effective approach to improve language function in chronic aphasia. However, it remains unclear what prognostic factors facilitate therapy response at the individual level. Here, we utilized data from the POLAR (Predicting Outcomes of Language Rehabilitation in Aphasia) trial to (a) determine therapy-induced change in confrontation naming and long-term maintenance of naming gains and (b) examine the extent to which aphasia severity, age, education, time postonset, and cognitive reserve predict naming gains at 1 week, 1 month, and 6 months posttherapy.
methodA total of 107 participants with chronic (≥ 12 months poststroke) aphasia underwent extensive case history, cognitive-linguistic testing, and a neuroimaging workup prior to receiving 6 weeks of impairment-based language therapy. Therapy-induced change in naming performance (measured as raw change on the 175-item Philadelphia Naming Test [PNT]) was assessed 1 week after therapy and at follow-up time points 1 month and 6 months after therapy completion. Change in naming performance over time was evaluated using paired
resultsNaming performance was improved by 5.9 PNT items (Cohen's
conclusionsThese results suggest that therapy-induced naming improvement is predictable based on several easily measurable prognostic factors. Broadly speaking, these results suggest that prognostication procedures in aphasia therapy can be improved and indicate that personalization of therapy is a realistic goal in the near future. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.22141829.
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