Evidence map›Paper›PMID 36827144›Full record

ArticleMarine drugs2023

Design, Synthesis, Antifungal Activity, and Molecular Docking of Streptochlorin Derivatives Containing the Nitrile Group.

Jing-Rui Liu, Ya Gao, Bing Jin, Dale Guo, Fang Deng, Qiang Bian, Hai-Feng Zhang, Xin-Ya Han, Abdallah S Ali, Ming-Zhi Zhang and 2 more

Abstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jing-Rui LiuJiangsu Key Laboratory of Pesticide Science, College of Sciences, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0001-6948-2528
Ya GaoJiangsu Key Laboratory of Pesticide Science, College of Sciences, Nanjing Agricultural University, Nanjing 210095, China.
Bing JinJiangsu Key Laboratory of Pesticide Science, College of Sciences, Nanjing Agricultural University, Nanjing 210095, China.
Dale GuoState Key Laboratory Breeding Base of Systematic Research Development and Utilization of Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Fang DengState Key Laboratory Breeding Base of Systematic Research Development and Utilization of Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Qiang BianNational Pesticide Engineering Research Center (Tianjin), College of Chemistry, Nankai University, Tianjin 300071, China.
Hai-Feng ZhangDepartment of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing 210095, China.
Xin-Ya HanSchool of Chemistry & Chemical Engineering, Anhui University of Technology, Ma'anshan 243002, China.
Abdallah S AliDepartment of Microbiology, Faculty of Agriculture, Cairo University, Giza 12613, Egypt.ORCID 0000-0003-2409-7452
Ming-Zhi ZhangJiangsu Key Laboratory of Pesticide Science, College of Sciences, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-8439-8989
Wei-Hua ZhangJiangsu Key Laboratory of Pesticide Science, College of Sciences, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0003-1994-5306
Yu-Cheng GuSyngenta Jealott's Hill International Research Centre, Bracknell RG42 6EY, Berkshire, UK.ORCID 0000-0002-6400-6167

Funding

National Natural Science Foundation of China 22177051, 32061143045
6 · The paper itself

Abstract

Based on the structures of natural products streptochlorin and pimprinine derived from marine or soil microorganisms, a series of streptochlorin derivatives containing the nitrile group were designed and synthesized through acylation and oxidative annulation. Evaluation for antifungal activity showed that compound

Indexed as

Antifungal AgentsFungicides, IndustrialIndolesMolecular Docking SimulationMolecular StructureOxazolesStructure-Activity RelationshipAntifungal AgentsFungicides, IndustrialIndolesOxazolesstreptochlorinantifungal activitymolecular dockingnitrile grouppimprinineSARstreptochlorinsynthesis

Identifiers

PMID36827144
PMCPMC9958711

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.