Evidence map›Paper›PMID 36827114›Full record

ArticleMarine drugs2023

Stellettin B Induces Cell Death in Bladder Cancer Via Activating the Autophagy/DAPK2/Apoptosis Signaling Cascade.

Chun-Han Chang, Bo-Jyun Lin, Chun-Han Chen, Nham-Linh Nguyen, Tsung-Han Hsieh, Jui-Hsin Su, Mei-Chuan Chen

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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  9. Review
  10. TM9SF1 promotes bladder cancer cell growth and infiltration.World journal of clinical oncology · 2024
    Article
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Chun-Han ChangSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.
Bo-Jyun LinDepartment of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Chun-Han ChenDepartment of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0001-6328-466X
Nham-Linh NguyenFaculty of Chemical and Food Technology, HCMC University of Technology and Education, Ho Chi Minh 70000, Vietnam.
Tsung-Han HsiehJoint Biobank, Office of Human Research, Taipei Medical University, Taipei 110, Taiwan.ORCID 0000-0002-2268-9246
Jui-Hsin SuDepartment of Science Education, National Museum of Marine Biology and Aquarium, Pingtung 944401, Taiwan.
Mei-Chuan ChenSchool of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan.
Taipei Medical University · TWHo Chi Minh City University of Technology and Engineering · VNNational Museum of Marine Biology and Aquarium · TWTaipei Medical University Hospital · TW

Funding

National Science and Technology Council of the Republic of China MOST 108-2320-B-038-027-MY3, MOST 109-2320-B-038-029 and MOST 111-2320-B-038 -032 -MY3
6 · The paper itself

Abstract

Bladder cancer (BC) is one of the most prevalent cancers worldwide. However, the recurrence rate and five-year survival rate have not been significantly improved in advanced BC, and new therapeutic strategies are urgently needed. The anticancer activity of stellettin B (SP-2), a triterpene isolated from the marine sponge

Indexed as

PoriferaTriterpenesUrinary Bladder NeoplasmsAnimalsApoptosisAutophagyCell Line, TumorDeath-Associated Protein KinasesProto-Oncogene Proteins c-aktDeath-Associated Protein KinasesProto-Oncogene Proteins c-aktstellettin BTriterpenesapoptosisautophagybladder cancerDAPK2stellettin B

Identifiers

PMID36827114
PMCPMC9966069
OpenAlexW4317740019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.