Evidence map›Paper›PMID 36826916›Full record

ArticleJournal of functional biomaterials2023

Tuning the Extracellular Vesicles Membrane through Fusion for Biomedical Applications.

Mamata Karmacharya, Sumit Kumar, Yoon-Kyoung Cho

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  15. Frontiers in medicine · 2024
    Article
  16. Review
  17. Extracellular Vesicles as Delivery Systems in Disease Therapy.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mamata KarmacharyaCenter for Soft and Living Matter, Institute for Basic Science (IBS), Ulsan 44919, Republic of Korea.
Sumit KumarCenter for Soft and Living Matter, Institute for Basic Science (IBS), Ulsan 44919, Republic of Korea.
Yoon-Kyoung ChoCenter for Soft and Living Matter, Institute for Basic Science (IBS), Ulsan 44919, Republic of Korea.ORCID 0000-0001-6423-1834

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Membrane fusion is one of the key phenomena in the living cell for maintaining the basic function of life. Extracellular vesicles (EVs) have the ability to transfer information between cells through plasma membrane fusion, making them a promising tool in diagnostics and therapeutics. This study explores the potential applications of natural membrane vesicles, EVs, and their fusion with liposomes, EVs, and cells and introduces methodologies for enhancing the fusion process. EVs have a high loading capacity, bio-compatibility, and stability, making them ideal for producing effective drugs and diagnostics. The unique properties of fused EVs and the crucial design and development procedures that are necessary to realize their potential as drug carriers and diagnostic tools are also examined. The promise of EVs in various stages of disease management highlights their potential role in future healthcare.

Indexed as

diagnosticsexosomefusionliposome

Identifiers

PMID36826916
PMCPMC9960107

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.