Evidence map›Paper›PMID 36826903›Full record

ArticleJournal of functional biomaterials2023

A Novel Dressing Composed of Adipose Stem Cells and Decellularized Wharton's Jelly Facilitated Wound Healing and Relieved Lymphedema by Enhancing Angiogenesis and Lymphangiogenesis in a Rat Model.

Jen-Her Lu, Kai Hsia, Chih-Kuan Su, Yi-Hsiang Pan, Hsu Ma, Shih-Hwa Chiou, Chih-Hsun Lin

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. A Novel Lymphosome-Based Long-Lasting Rat Tail Model of Lymphedema.Journal of reconstructive microsurgery · 2026
    Article
  3. [Research on tissue regeneration and engineered scaffold materials in prevention and treatment of lymphedema].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Review
  4. Article
  5. Review
  6. Host angiogenic reprogramming byFrontiers in microbiology · 2025
    Article
  7. Review
  8. Article
  9. [Research advances on stem cell-based treatments in animal studies and clinical trials of lymphedema].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jen-Her LuDepartment of Pediatrics, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0003-2056-3065
Kai HsiaDepartment of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0003-0370-4698
Chih-Kuan SuDivision of Plastic and Reconstructive Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Yi-Hsiang PanDivision of Plastic and Reconstructive Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Hsu MaDivision of Plastic and Reconstructive Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Shih-Hwa ChiouDepartment of Medical Research, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Chih-Hsun LinDivision of Plastic and Reconstructive Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-9771-5816
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TWTaipei Medical University Hospital · TW

Funding

Taipei Veterans General Hospital V112C-186Taiwan Ministry of Science and Technology 109WHA0110184 and MOST 109-2314-B-038-143
6 · The paper itself

Abstract

Lymphedema causes tissue swelling due to the accumulation of lymphatic fluid in the tissue, which delays the process of wound-healing. Developing effective treatment options of lymphedema is still an urgent issue. In this study, we aim to fabricate tissue-engineered moist wound dressings with adipose stem cells (ASCs) and decellularized Wharton's jelly (dWJ) from the human umbilical cord in order to ameliorate lymphedema. Rat ASCs were proliferated and an apparent layer was observed on dWJ at day 7 and 14. A rat tail lymphedema model was developed to evaluate the efficacy of the treatment. Approximately 1 cm of skin near the base of the rat tail was circularly excised. The wounds were treated by secondary healing (control) (

Indexed as

angiogenesisdecellularized Wharton’s jellylymphangiogenesislymphedemarat adipose stem cellwound-healing

Identifiers

PMID36826903
PMCPMC9960849
OpenAlexW4320729491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.