Evidence map›Paper›PMID 36826887›Full record

ArticleJournal of functional biomaterials2023

An Assessment of Blood Vessel Remodeling of Nanofibrous Poly(ε-Caprolactone) Vascular Grafts in a Rat Animal Model.

Jana Horakova, Tereza Blassova, Zbynek Tonar, Connor McCarthy, Katerina Strnadova, David Lukas, Petr Mikes, Patrick Bowen, Roger Guillory, Megan Frost and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Jana HorakovaDepartment of Nonwoven and Nanofibrous Materials, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic.ORCID 0000-0003-2926-0570
Tereza BlassovaDepartment of Histology and Embryology and Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Karlovarska 48, 301 66 Pilsen, Czech Republic.
Zbynek TonarDepartment of Histology and Embryology and Biomedical Centre, Faculty of Medicine in Pilsen, Charles University, Karlovarska 48, 301 66 Pilsen, Czech Republic.ORCID 0000-0002-7200-9894
Connor McCarthyDepartment of Biomedical Engineering, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
Katerina StrnadovaDepartment of Chemistry-Bioengineering, Faculty of Science, Humanities and Education, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic.ORCID 0000-0001-8617-9547
David LukasDepartment of Chemistry-Bioengineering, Faculty of Science, Humanities and Education, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic.
Petr MikesDepartment of Physics, Faculty of Science, Humanities and Education, Technical University of Liberec, Studentska 1402/2, 461 17 Liberec, Czech Republic.
Patrick BowenDepartment of Materials Science and Engineering, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
Roger GuilloryDepartment of Biomedical Engineering, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
Megan FrostDepartment of Biomedical Engineering, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
Jeremy GoldmanDepartment of Biomedical Engineering, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.
Michigan Technological University · USTechnical University of Liberec · CZCharles University · CZ

Funding

Fulbright Czech Republic Fulbright Czech Republic
6 · The paper itself

Abstract

The development of an ideal vascular prosthesis represents an important challenge in terms of the treatment of cardiovascular diseases with respect to which new materials are being considered that have produced promising results following testing in animal models. This study focuses on nanofibrous polycaprolactone-based grafts assessed by means of histological techniques 10 days and 6 months following suturing as a replacement for the rat aorta. A novel stereological approach for the assessment of cellular distribution within the graft thickness was developed. The cellularization of the thickness of the graft was found to be homogeneous after 10 days and to have changed after 6 months, at which time the majority of cells was discovered in the inner layer where the regeneration of the vessel wall was found to have occurred. Six months following implantation, the endothelialization of the graft lumen was complete, and no

Indexed as

electrospinninghistological evaluationpolycaprolactonestereologyvascular graftvascular remodeling

Identifiers

PMID36826887
PMCPMC9965469
OpenAlexW4319297251

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.