Evidence map›Paper›PMID 36826871›Full record

ArticleJournal of functional biomaterials2023

Anthocyanin/Honey-Incorporated Alginate Hydrogel as a Bio-Based pH-Responsive/Antibacterial/Antioxidant Wound Dressing.

Faezeh Lotfinia, Mohammad-Reza Norouzi, Laleh Ghasemi-Mobarakeh, Mohammadreza Naeimirad

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Faezeh LotfiniaDepartment of Textile Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran.
Mohammad-Reza NorouziDepartment of Textile Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran.ORCID 0000-0002-0212-3595
Laleh Ghasemi-MobarakehDepartment of Textile Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran.
Mohammadreza NaeimiradDepartment of Materials and Textile Engineering, Faculty of Engineering, Razi University, Kermanshah 67144-14971, Iran.ORCID 0000-0003-3138-7431
Isfahan University of Technology · IRRazi University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection is a major problem that increases the normal pH of the wound bed and interferes with wound healing. Natural biomaterials can serve as a suitable environment to acquire a great practical effect on the healing process. In this context, anthocyanin-rich red cabbage (Brassica oleracea var. capitata F. rubra) extract and honey-loaded alginate hydrogel was fabricated using calcium chloride as a crosslinking agent. The pH sensitivity of anthocyanins can be used as an indicator to monitor possible infection of the wound, while honey would promote the healing process by its intrinsic properties. The mechanical properties of the hydrogel film samples showed that honey acts as a plasticizer and that increasing the incorporation from 200% to 400% enhances the tensile strength from 3.22 to 6.15 MPa and elongation at break from 0.69% to 4.75%. Moreover, a water absorption and retention study showed that the hydrogel film is able to absorb about 250% water after 50 min and retain 40% of its absorbed water after 12 h. The disk diffusion test showed favorable antibacterial activity of the honey-loaded hydrogel against both Gram-positive and Gram-negative

Indexed as

alginate hydrogelanthocyaninantibacterial wound dressingantioxidanthoneypH-responsive

Identifiers

PMID36826871
PMCPMC9961009
OpenAlexW4318586788

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.