Evidence map›Paper›PMID 36826867›Full record

ArticleJournal of functional biomaterials2023

Chitosan/Phenolic Compounds Scaffolds for Connective Tissue Regeneration.

Beata Kaczmarek-Szczepańska, Izabela Polkowska, Katarzyna Paździor-Czapula, Beata Nowicka, Magdalena Gierszewska, Marta Michalska-Sionkowska, Iwona Otrocka-Domagała

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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  6. Application Potential ofFoods (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Beata Kaczmarek-SzczepańskaDepartment of Biomaterials and Cosmetic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Torun, Gagarin 7, 87-100 Toruń, Poland.ORCID 0000-0002-2563-2376
Izabela PolkowskaDepartment and Clinic of Animal Surgery, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland.
Katarzyna Paździor-CzapulaDepartment of Pathological Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-719 Olsztyn, Poland.ORCID 0000-0002-7661-7993
Beata NowickaDepartment and Clinic of Animal Surgery, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland.ORCID 0000-0003-1240-323X
Magdalena GierszewskaDepartment of Physical Chemistry and Polymer Physical Chemistry, Faculty of Chemistry, Nicolaus Copernicus University in Torun, Gagarin 7, 87-100 Toruń, Poland.ORCID 0000-0001-8935-4857
Marta Michalska-SionkowskaDepartment of Environmental Microbiology and Biotechnology, Faculty of Biology and Veterinary Science, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Torun, Poland.ORCID 0000-0002-5851-734X
Iwona Otrocka-DomagałaDepartment of Pathological Anatomy, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 13, 10-719 Olsztyn, Poland.ORCID 0000-0002-3271-0408
Nicolaus Copernicus University · PLUniversity of Life Sciences in Lublin · PLUniversity of Warmia and Mazury in Olsztyn · PL

Funding

Nicolaus Copernicus University 282/2021
6 · The paper itself

Abstract

Chitosan-based scaffolds modified by gallic acid, ferulic acid, and tannic acid were fabricated. The aim of the experiment was to compare the compatibility of scaffolds based on chitosan with gallic acid, ferulic acid, or tannic acid using the in vivo method. For this purpose, materials were implanted into rabbits in the middle of the latissimus dorsi muscle length. A scaffold based on unmodified chitosan was implanted by the same method as a control. Moreover, the Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR) spectra and scanning electron microscope (SEM) observations were made to study the interactions between chitosan and phenolic acids. Additionally, antioxidant properties and blood compatibility were investigated. The results showed that all studied materials were safe and non-toxic. However, chitosan scaffolds modified by gallic acid and tannic acid were resorbed faster and, as a result, tissues were organized faster than those modified by ferulic acid or unmodified.

Indexed as

chitosanhistological assessmentin vivophenolic acids

Identifiers

PMID36826867
PMCPMC9958647
OpenAlexW4318483161

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.