Evidence map›Paper›PMID 36826863›Full record

ReviewJournal of functional biomaterials2023

Combination of Enzymes with Materials to Give Them Antimicrobial Features: Modern Trends and Perspectives.

Elena Efremenko, Nikolay Stepanov, Aysel Aslanli, Ilya Lyagin, Olga Senko, Olga Maslova

Open access · goldAbstract readReview
In one paragraph

Review in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Biochemistry and biophysics reports · 2025
    Article
  2. Review
  3. Enhancing the destruction ofFrontiers in cellular and infection microbiology · 2025
    Article
  4. Synthesis of Pt-MoSRSC advances · 2024
    Article
  5. Review
  6. Various Biomimetics, Including Peptides as Antifungals.Biomimetics (Basel, Switzerland) · 2023
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elena EfremenkoFaculty of Chemistry, Lomonosov Moscow State University, Lenin Hills 1/3, 119991 Moscow, Russia.ORCID 0000-0002-6992-854X
Nikolay StepanovFaculty of Chemistry, Lomonosov Moscow State University, Lenin Hills 1/3, 119991 Moscow, Russia.ORCID 0000-0003-0821-8226
Aysel AslanliFaculty of Chemistry, Lomonosov Moscow State University, Lenin Hills 1/3, 119991 Moscow, Russia.ORCID 0000-0003-1087-6690
Ilya LyaginFaculty of Chemistry, Lomonosov Moscow State University, Lenin Hills 1/3, 119991 Moscow, Russia.ORCID 0000-0002-3970-4334
Olga SenkoFaculty of Chemistry, Lomonosov Moscow State University, Lenin Hills 1/3, 119991 Moscow, Russia.ORCID 0000-0001-7831-6222
Olga MaslovaFaculty of Chemistry, Lomonosov Moscow State University, Lenin Hills 1/3, 119991 Moscow, Russia.ORCID 0000-0002-6358-1231
Lomonosov Moscow State University · RU

Funding

State Task of Lomonosov Moscow State University 121041500039-8State Task of N.M. Emanuel Institute of Biochemical Physics RAS 01201253305
6 · The paper itself

Abstract

Multidrug-resistant bacteria form serious problems in many areas, including medicine and the food industry. At the same time, great interest is shown in the transfer or enhancement of antimicrobial properties to various materials by modifying them with enzymes. The use of enzymes in biomaterials with antimicrobial properties is important because enzymes can be used as the main active components providing antimicrobial properties of functionalized composite biomaterials, or can serve as enhancers of the antimicrobial action of certain substances (antibiotics, antimicrobial peptides, metal nanoparticles, etc.) against cells of various microorganisms. Enzymes can simultaneously widen the spectrum of antimicrobial activity of biomaterials. This review presents the most promising enzymes recently used for the production of antibacterial materials, namely hydrolases and oxidoreductases. Computer modeling plays an important role in finding the most effective combinations between enzymes and antimicrobial compounds, revealing their possible interactions. The range of materials that can be functionalized using enzymes looks diverse. The physicochemical characteristics and functionalization methods of the materials have a significant impact on the activity of enzymes. In this context, fibrous materials are of particular interest. The purpose of this review is to analyze the current state of the art in this area.

Indexed as

antibioticsantimicrobial peptidesbiocompatibilitycomputational modelingfunctionalized materialshydrolysesimmobilizationlactonasesmetal nanoparticlesoxidoreductases

Identifiers

PMID36826863
PMCPMC9960987
OpenAlexW4318052253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.