Evidence map›Paper›PMID 36826714›Full record

ArticleSports medicine (Auckland, N.Z.)2023

Should We be Concerned with Nicotine in Sport? Analysis from 60,802 Doping Control Tests in Italy.

Thomas Zandonai, Francesco Botrè, Maria Gabriella Abate, Ana María Peiró, Toby Mündel

Open access · hybridAbstract read
In one paragraph

Article in Sports medicine (Auckland, N.Z.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 5 countries.

Thomas ZandonaiDepartment of Pharmacology, Paediatrics and Organic Chemistry, Miguel Hernández University of Elche, Crta. Nacional, N-332. S/N, Sant Joan, 03550, Alicante, Spain. tzandonai@umh.es.ORCID 0000-0002-7606-9675
Francesco BotrèLaboratorio Antidoping, Federazione Medico Sportiva Italiana, Rome, Italy.ORCID 0000-0001-5296-8126
Maria Gabriella AbateLaboratorio Antidoping, Federazione Medico Sportiva Italiana, Rome, Italy.
Ana María PeiróNeuropharmacology on Pain and Functional Diversity (NED), Institute of Health and Biomedical Research of Alicante (ISABIAL Foundation), Alicante, Spain.ORCID 0000-0002-2385-3749
Toby MündelSchool of Sport, Exercise and Nutrition, Massey University, Palmerston North, New Zealand.ORCID 0000-0002-4214-8543
Federazione Medico Sportiva Italiana · ITBrock University · CAHospital General Universitario de Alicante Doctor Balmis · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNicotine is a psychostimulant drug with purported use in sports environments, though the use of nicotine among athletes has not been studied extensively.

objectiveThe aim of this study was to assess the nicotine positivity rate in 60,802 anti-doping urine samples from 2012 to 2020.

methodsUrine samples obtained in-competition at different national and international sports events held in Italy during the period 2012-2020 were analysed. All samples were from anonymous athletes that were collected and analysed at the WADA-accredited antidoping laboratory in Rome, Italy. Samples were analysed by gas chromatography coupled with mass spectrometry, with a cut-off concentration for nicotine of > 50 ng/mL. Results were stratified by year, sport and sex.

resultsAn overall mean of 22.7% of the samples (n = 13,804; males: n = 11,099; females: n = 2705) showed nicotine intake, with male samples also displaying higher positivity rates than female (24.1% vs 18.5%). Sample positivity was higher during 2012-2014 (25-33%) than 2015-2020 (15-20%). Samples from team sports displayed a higher positivity rate than those from individual sports (31.4 vs 14.1%).

conclusionsThe current data demonstrates that one in five samples from a range of 90 sports test positive for nicotine in-competition. There is a lower positivity rate in endurance versus power/strength athletes and higher positivity rate in team versus individual sports, probably accounted for by differences in physiological and psychological demands and the desire for socialisation. WADA, international and national sports federations should consider these findings with concern, proactively investigate this phenomenon and act in order to protect the health and welfare of its athletes.

Indexed as

Central Nervous System StimulantsDoping in SportsSportsAthletesFemaleHumansItalyMaleNicotineCentral Nervous System StimulantsNicotine

Identifiers

PMID36826714
PMCPMC9951140
OpenAlexW4321748511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.