Evidence map›Paper›PMID 36826681›Full record

ReviewMolecular biology reports2023

Recent advances on genome-wide association studies (GWAS) and genomic selection (GS); prospects for Fusarium head blight research in Durum wheat.

Zahoor Ahmad Mir, Tilak Chandra, Anurag Saharan, Neeraj Budhlakoti, D C Mishra, M S Saharan, Reyazul Rouf Mir, Amit Kumar Singh, Soumya Sharma, V K Vikas and 1 more

Abstract readReview
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In one paragraph

Review in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Zahoor Ahmad MirICAR-National Bureau of Plant Genetic Resources, New Delhi, 110012, India.
Tilak ChandraICAR-Indian Agricultural Statistics Research Institute, New Delhi, 110012, India.
Anurag SaharanICAR-Indian Agricultural Research Institute, New Delhi, 110012, India.
Neeraj BudhlakotiICAR-Indian Agricultural Statistics Research Institute, New Delhi, 110012, India.
D C MishraICAR-Indian Agricultural Statistics Research Institute, New Delhi, 110012, India.
M S SaharanICAR-Indian Agricultural Research Institute, New Delhi, 110012, India.
Reyazul Rouf MirDivision of Genetics and Plant Breeding, Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir (SKUAST-Kashmir), Srinagar, Jammu Kashmir, 190025, India.
Amit Kumar SinghICAR-National Bureau of Plant Genetic Resources, New Delhi, 110012, India.
Soumya SharmaICAR-Indian Agricultural Statistics Research Institute, New Delhi, 110012, India.
V K VikasICAR- Indian Agricultural Research Institute, Regional Station, Wellington, The Nilgiris, Tamilnadu, 643231, India. vikaswtn21@gmail.com.
Sundeep KumarICAR-National Bureau of Plant Genetic Resources, New Delhi, 110012, India. Sundeep.Kumar@icar.gov.in.ORCID http://orcid.org/0000-0001-5917-8290
Indian Agricultural Statistics Research Institute · INNational Bureau of Plant Genetic Resources · INIndian Agricultural Research Institute · INIndian Council of Agricultural Research · INSher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWheat is an important cereal crop that is cultivated in different parts of the world. The biotic stresses are the major concerns in wheat-growing nations and are responsible for production loss globally. The change in climate dynamics makes the pathogen more virulent in foothills and tropical regions. There is growing concern about FHB in major wheat-growing nations, and until now, there has been no known potential source of resistance identified in wheat germplasm. The plant pathogen interaction activates the cascade of pathways, genes, TFs, and resistance genes. Pathogenesis-related genes' role in disease resistance is functionally validated in different plant systems. Similarly, Genomewide association Studies (GWAS) and Genomic selection (GS) are promising tools and have led to the discovery of resistance genes, genomic regions, and novel markers. Fusarium graminearum produces deoxynivalenol (DON) mycotoxins in wheat kernels, affecting wheat productivity globally. Modern technology now allows for detecting and managing DON toxin to reduce the risk to humans and animals. This review offers a comprehensive overview of the roles played by GWAS and Genomic selection (GS) in the identification of new genes, genetic variants, molecular markers and DON toxin management strategies.

methodsThe review offers a comprehensive and in-depth analysis of the function of Fusarium graminearum virulence factors in Durum wheat. The role of GWAS and GS for Fusarium Head Blight (FHB) resistance has been well described. This paper provides a comprehensive description of the various statistical models that are used in GWAS and GS. In this review, we look at how different detection methods have been used to analyze and manage DON toxin exposure.

resultsThis review highlights the role of virulent genes in Fusarium disease establishment. The role of genome-based selection offers the identification of novel QTLs in resistant wheat germplasm. The role of GWAS and GS selection has minimized the use of population development through breeding technology. Here, we also emphasized the function of recent technological developments in minimizing the impact of DON toxins and their implications for food safety.

Indexed as

FusariumTriticumGenome-Wide Association StudyGenomicsHumansPlant BreedingPlant DiseasesDON toxinFusarium graminearumGSGWASTriticum durum

Identifiers

PMID36826681
OpenAlexW4321748386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.