Evidence map›Paper›PMID 36826601›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

New technology using crystalline lens autofluorescence for presbyopia and cataract grading.

Youngsub Eom, Young-Woo Suh, Seong-Woo Kim, Young Joo Lee, Hyun Sun Jeon, Suk Yeon Lee, Ik Hyun Lee, Jong Suk Song, Hyo Myung Kim

Abstract read
PubMed Publisher
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Macular pigment evaluation using dual-wavelength fundus auto-fluorescence imaging.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Youngsub Eom *Department of Ophthalmology, Korea University Ansan Hospital, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, 15355, South Korea. hippotate@hanmail.net.ORCID http://orcid.org/0000-0001-9475-4409
Young-Woo Suh *Department of Ophthalmology, Korea University Ansan Hospital, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, 15355, South Korea. forgod77@korea.ac.kr.
Seong-Woo KimDepartment of Ophthalmology, Korea University College of Medicine, Seoul, Republic of Korea.
Young Joo LeeDepartment of Ophthalmology, Korea University Ansan Hospital, 123, Jeokgeum-ro, Danwon-gu, Ansan-si, Gyeonggi-do, 15355, South Korea.
Hyun Sun JeonDepartment of Ophthalmology, Korea University College of Medicine, Seoul, Republic of Korea.
Suk Yeon LeeDepartment of Ophthalmology, Korea University College of Medicine, Seoul, Republic of Korea.
Ik Hyun LeeDepartment of Mechatronics Engineering, Tech University of Korea, Siheung, Gyeonggi-do, Republic of Korea.
Jong Suk SongDepartment of Ophthalmology, Korea University College of Medicine, Seoul, Republic of Korea.
Hyo Myung KimDepartment of Ophthalmology, Korea University College of Medicine, Seoul, Republic of Korea.
Korea University · KREmory University · US

Funding

Korea Environment Industry & Technology Institute(KEITI) through Technology Development Project for Safety Management of Household Chemical Products, funded by Korea Ministry of Environment(MOE) 2020002960007, NTIS-1485017544Korea Medical Device Development Fund grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, the Ministry of Food and Drug Safety) Project Number: 9991007583, KMDF_PR_20200901_0296Korea University Ansan Hospital grant K1625491, K1722121, K1811051, K1913161, and K2010921Korea University Grant K1625491, K1722121, K1811051, K1913161, and K2010921SNUBH Research Fund grant numbers 13-2020-007Technology development Program(S3305836) funded by the Ministry of SMEs and Startups(MSS, Korea) S3305836The National Research Foundation of Korea(NRF) grant funded by the Korea government(MSIT) NRF-2021R1F1A1062017).The Priority Research Centers Program under the grant number (2017R1A6A1A03015562) through the National Research Foundation of Korea (NRF) under the Ministry of Education 2017R1A6A1A03015562The Technology development Program(S3127902) funded by the Ministry of SMEs and Startups(MSS, Korea) S3127902TRC Research Grant of the Korea University Medicine and Korea Institute of Science and Technology (K2107901) K2107901
6 · The paper itself

Abstract

purposeTo investigate  whether fundus autofluorescence (FAF) obtained using an ultra-wide field (UWF) fundus camera with an artificial opacity pattern can grade the degree of presbyopia and nuclear cataract.

methodsSixty eyes of 30 patients were enrolled in this prospective diagnostic study. The nuclear cataract (nuclear color/opalescence (NC/NO)) was graded according to the Lens Opacity Classification System III. The monocular near point of accommodation (NPA) was measured in eyes with NC3/NO3 or less. The mean gray value difference between the central 8 artificial opacity lesions and peripheral 8 artificial opacity lesions in the retinal AF was measured. The correlation between the mean gray value difference, NPA, and nuclear cataract grade was analyzed.

resultsThe mean nuclear cataract grade of 60 eyes was 3.2 ± 1.6 and mean NPA of 37 eyes was 45.3 ± 16.1 cm. The mean gray value differences increased with increasing nuclear cataract grade (eyes with NC/NO grade 1, 53.3 ± 11.4; 2, 78.3 ± 13.6; 3, 95.2 ± 12.2; 4, 101.6 ± 11.9; 5, 109.0 ± 22.9; and 6, 121.1 ± 12.0; p < 0.001). The mean gray value difference was positively correlated with both the monocular NPA (R

conclusionsThe FAF camera with an artificial opacity pattern attached can be used to effectively diagnose the degree of presbyopia and nuclear cataract.

Indexed as

CataractLens, CrystallinePresbyopiaHumansProspective StudiesTechnologyAutofluorescenceCataractCrystalline lensDiagnosisPresbyopia

Identifiers

PMID36826601
OpenAlexW4321748988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.