Evidence map›Paper›PMID 36826589›Full record

Observational studyEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2023

Interinstitutional analysis of the outcome after surgery for type A aortic dissection.

Fausto Biancari, Angelo M Dell'Aquila, Giuseppe Gatti, Andrea Perrotti, Amélie Hervé, Joseph Touma, Matteo Pettinari, Sven Peterss, Joscha Buech, Konrad Wisniewski and 30 more

Registry-linked trialAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04831073 (European Registry of Type A Aortic Dissection), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04831073 completednot on this map

European Registry of Type A Aortic Dissection

TypeobservationalSponsorHelsinki University Central HospitalRan2023 to 2024Enrolled3,902ConditionsType A Aortic DissectionArmsSurgery on the ascending aorta with or without repair of the aortic root and/or aortic arch
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Outcome After Surgery for Type A Intramural Hematoma.Journal of cardiovascular development and disease · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

Fausto BiancariHeart and Lung Center, Helsinki University Hospital, University of Helsinki, 00029, Helsinki, Finland. faustobiancari@yahoo.it.ORCID http://orcid.org/0000-0001-5028-8186
Angelo M Dell'AquilaDepartment of Cardiothoracic Surgery, University Hospital Muenster, Muenster, Germany.
Giuseppe GattiDivision of Cardiac Surgery, Cardio-Thoracic and Vascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
Andrea PerrottiDepartment of Thoracic and Cardiovascular Surgery, University of Franche-Comte, Besancon, France.
Amélie HervéDepartment of Thoracic and Cardiovascular Surgery, University of Franche-Comte, Besancon, France.
Joseph ToumaDepartment of Vascular Surgery, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, Creteil, France.
Matteo PettinariDepartment of Cardiac Surgery, Ziekenhuis Oost Limburg, Genk, Belgium.
Sven PeterssLMU University Hospital, Ludwig Maximilian University, Munich, Germany.
Joscha BuechLMU University Hospital, Ludwig Maximilian University, Munich, Germany.
Konrad WisniewskiDepartment of Cardiothoracic Surgery, University Hospital Muenster, Muenster, Germany.
Tatu JuvonenHeart and Lung Center, Helsinki University Hospital, University of Helsinki, 00029, Helsinki, Finland.
Mikko JormalainenHeart and Lung Center, Helsinki University Hospital, University of Helsinki, 00029, Helsinki, Finland.
Caius MustonenHeart and Lung Center, Helsinki University Hospital, University of Helsinki, 00029, Helsinki, Finland.
Andreas RukosujewDepartment of Cardiothoracic Surgery, University Hospital Muenster, Muenster, Germany.
Till DemalDepartment of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Lenard ConradiDepartment of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
Marek PolDepartment of Cardiac Surgery, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic.
Petr KacerDepartment of Cardiac Surgery, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic.
Francesco OnoratiDivision of Cardiac Surgery, University of Verona Medical School, Verona, Italy.
Cecilia RossettiDivision of Cardiac Surgery, University of Verona Medical School, Verona, Italy.
Igor VendraminCardiothoracic Department, University Hospital, Udine, Italy.
Daniela PianiCardiothoracic Department, University Hospital, Udine, Italy.
Mauro RinaldiCardiac Surgery, Molinette Hospital, University of Turin, Turin, Italy.
Luisa FerranteCardiac Surgery, Molinette Hospital, University of Turin, Turin, Italy.
Eduard QuintanaDepartment of Cardiovascular Surgery, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain.
Robert Pruna-GuillenDepartment of Cardiovascular Surgery, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain.
Javier Rodriguez LegaCardiovascular Surgery Department, University Hospital Gregorio Marañón, Madrid, Spain.
Angel G PintoCardiovascular Surgery Department, University Hospital Gregorio Marañón, Madrid, Spain.
Metesh AcharyaDepartment of Cardiac Surgery, Glenfield Hospital, Leicester, UK.
Zein El-DeanDepartment of Cardiac Surgery, Glenfield Hospital, Leicester, UK.
Mark FieldLiverpool Centre for Cardiovascular Sciences, Liverpool Heart and Chest Hospital, Liverpool, UK.
Amer HarkyLiverpool Centre for Cardiovascular Sciences, Liverpool Heart and Chest Hospital, Liverpool, UK.
Manoj KuduvalliLiverpool Centre for Cardiovascular Sciences, Liverpool Heart and Chest Hospital, Liverpool, UK.
Francesco NappiDepartment of Cardiac Surgery, Centre Cardiologique du Nord de Saint-Denis, Paris, France.
Sebastien GerelliCentre Hospitalier Annecy Genevois, Épagny-Metz-Tessy, France.
Dario Di PernaCentre Hospitalier Annecy Genevois, Épagny-Metz-Tessy, France.
Enzo MazzaroDivision of Cardiac Surgery, Cardio-Thoracic and Vascular Department, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
Stefano RosatoCenter for Global Health, National Health Institute, Rome, Italy.
Antonio FioreDepartment of Cardiac Surgery, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, Creteil, France.
Giovanni MariscalcoDepartment of Cardiac Surgery, Glenfield Hospital, Leicester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the impact of individual institutions on the outcome after surgery for Stanford type A aortic dissection (TAAD).

methodsThis is an observational, multicenter, retrospective cohort study including 3902 patients who underwent surgery for TAAD at 18 university and non-university hospitals.

resultsLogistic regression showed that four hospitals had increased risk of in-hospital mortality, while two hospitals were associated with decreased risk of in-hospital mortality. Risk-adjusted in-hospital mortality rates were lower in four hospitals and higher in other four hospitals compared to the overall in-hospital mortality rate (17.7%). Participating hospitals were classified as overperforming or underperforming if their risk-adjusted in-hospital mortality rate was lower or higher than the in-hospital mortality rate of the overall series, respectively. Propensity score matching yielded 1729 pairs of patients operated at over- or underperforming hospitals. Overperforming hospitals had a significantly lower in-hospital mortality (12.8% vs. 22.2%, p < 0.0001) along with decreased rate of stroke and/or global brain ischemia (16.5% vs. 19.9%, p = 0.009) compared to underperforming hospitals. Aggregate data meta-regression of the results of participating hospitals showed that hospital volume was inversely associated with in-hospital mortality (p = 0.043). Hospitals with an annual volume of less than 15 cases had an increased risk of in-hospital mortality (adjusted OR, 1.345, 95% CI 1.126-1.607).

conclusionThe present findings indicate that there are significant differences between hospitals in terms of early outcome after surgery for TAAD. Low hospital volume may be a determinant of poor outcome of TAAD.

trial registrationClinicalTrials.gov Identifier: NCT04831073.

Indexed as

Aortic DissectionAzidesDeoxyglucoseHospital MortalityHospitalsHumansRetrospective StudiesTreatment Outcome1,3,4,6-tetra-O-acetyl-2-azido-2-deoxyglucopyranoseAzidesDeoxyglucoseAortic dissectionType A aortic dissectionVolume

Identifiers

PMID36826589
PMCPMC10449993

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.