Evidence map›Paper›PMID 36826582›Full record

ArticleJournal of cardiovascular development and disease2023

Intracoronary Administration of Microencapsulated HGF in a Reperfused Myocardial Infarction Swine Model.

Virginia Blanco-Blázquez, Claudia Báez-Díaz, Francisco Miguel Sánchez-Margallo, Irene González-Bueno, Helena Martín, Rebeca Blázquez, Javier G Casado, Alejandra Usón, Julia Solares, Itziar Palacios and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Virginia Blanco-BlázquezCardiovascular Area, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.ORCID 0000-0003-1971-919X
Claudia Báez-DíazCardiovascular Area, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.ORCID 0000-0001-9031-2929
Francisco Miguel Sánchez-MargalloCardiovascular Area, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.ORCID 0000-0003-2138-988X
Irene González-BuenoCardiovascular Area, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.
Helena MartínCardiovascular Area, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.
Rebeca BlázquezCentro de Investigación Biomédica En Red de Enfermedades Cardiovasculares CIBERCV, 28029 Madrid, Spain.
Javier G CasadoCentro de Investigación Biomédica En Red de Enfermedades Cardiovasculares CIBERCV, 28029 Madrid, Spain.ORCID 0000-0001-6797-7287
Alejandra UsónStem Cell Therapy Unit, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.
Julia SolaresSan Pedro Alcántara Hospital, 10004 Cáceres, Spain.
Itziar PalaciosCoretherapix (Tigenix Group, Takeda), 28046 Madrid, Spain.
Rob SteendamInnocore Pharmaceuticals, 9713 GX Groningen, The Netherlands.
Verónica CrisóstomoCardiovascular Area, Jesús Usón Minimally Invasive Surgery Centre, 10071 Cáceres, Spain.ORCID 0000-0003-1740-7029
Centro de Investigación en Red en Enfermedades Cardiovasculares · ESCentro de Cirugía de Mínima Invasión Jesús Usón · ESHospital San Pedro de Alcántara · ESTiGenix (Spain) · ES

Funding

Agencia Estatal de Investigación PID2019-107329RAC22/AEI/10.13039/501100011033Instituto de Salud Carlos III PI20/00247Junta de Extremadura, Consejeria de Economía e Infraestructuras GR18199Junta de Extremadura, Consejeria de Economía e Infraestructuras IB20191
6 · The paper itself

Abstract

Therapy microencapsulation allows minimally invasive, safe, and effective administration. Hepatocyte growth factor (HGF) has angiogenic, anti-inflammatory, anti-apoptotic, and anti-fibrotic properties. Our objective was to evaluate the cardiac safety and effectiveness of intracoronary (IC) administration of HGF-loaded extended release microspheres in an acute myocardial infarction (AMI) swine model. An IC infusion of 5 × 10

Indexed as

hepatocyte growth factormicroencapsulationmyocardial infarctionswine model

Identifiers

PMID36826582
PMCPMC9960949
OpenAlexW4321253267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.