Evidence map›Paper›PMID 36826577›Full record

ArticleJournal of cardiovascular development and disease2023

Elevated Levels of Neutrophil-to Monocyte Ratio Are Associated with the Initiation of Paroxysmal Documented Atrial Fibrillation in the First Two Months after Heart Transplantation: A Uni-Institutional Retrospective Study.

Dragos-Florin Baba, Horatiu Suciu, Calin Avram, Manuela Gyorgy, Alina Danilesco, Laurentiu Huma, Ileana Anca Sin

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Editorial: Blood biomarkers in cardiovascular diseases.Frontiers in cardiovascular medicine · 2025
    Article
  5. Leukocyte dynamics inFrontiers in immunology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dragos-Florin BabaEmergency Institute for Cardiovascular Diseases and Transplantation, 540142 Targu Mures, Romania.ORCID 0000-0002-4004-9648
Horatiu SuciuEmergency Institute for Cardiovascular Diseases and Transplantation, 540142 Targu Mures, Romania.
Calin AvramDepartment of Medical Informatics and Biostatistics, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania.ORCID 0000-0003-1488-3329
Manuela GyorgyDepartment of Psychology, Dimitrie Cantemir University, 999032 Bucharest, Romania.
Alina DanilescoDepartment of Cell and Molecular Biology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania.
Laurentiu HumaEmergency Institute for Cardiovascular Diseases and Transplantation, 540142 Targu Mures, Romania.ORCID 0000-0002-9413-7803
Ileana Anca SinDepartment of Cell and Molecular Biology, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania.
Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · RODimitrie Cantemir University · RO

Funding

This work was supported by the University of Medicine, Pharmacy, Science and Technology "George Emil Palade" of Târgu Mureș, Research Grant number 511/1/17.01.2022. Research Grant number 511/1/17.01.2022
6 · The paper itself

Abstract

backgroundHeart transplantation represents the treatment for patients with end-stage heart failure (HF) being symptomatic despite optimal medical therapy. We investigated the role of NMR (neutrophil-to-monocyte ratio), NLR (neutrophil-to-lymphocyte ratio), NPR (neutrophil-to-platelet ratio), NWR (neutrophil-to-white cells ratio), MLR (monocyte-to-lymphocyte ratio), PLR (platelet-to-lymphocyte ratio), MWR (neutrophil-to-white cells ratio), and LWR (lymphocyte-to-white cells ratio) at the same cut-off values previously studied, to predict complications after heart transplant within 2 months after surgery.

methodsFrom May 2014 to January 2021, was included 38 patients in our study from the Cardiovascular and Transplant Emergency Institute of Târgu Mureș.

resultsPreoperative NMR > 8.9 (OR: 70.71, 95% CI: 3.39-1473.64;

conclusionPreoperative elevated levels of NMR were associated with the apparition of documented AFib, with high levels of MWR as a protective factor. High MWR was a risk factor in developing complications of any cause in the first 2 months after heart transplantation.

Indexed as

atrial fibrillationheart transplantinflammationmonocyte-to-white cells rationeutrophil-to-monocyte ratio

Identifiers

PMID36826577
PMCPMC9960862
OpenAlexW4320917718

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.