Evidence map›Paper›PMID 36826491›Full record

ArticleCardiovascular and interventional radiology2023

A Retrospective Comparison of the Efficacy of Embolization with Imipenem/Cilastatin and Microspheres in the Management of Chronic Shoulder Pain.

Mathieu Finas, Julien Frandon, Emeric Gremen, Clément Horteur, Michaël Benassayag, Gabriel Lateur, Régis Pailhe, Gilbert Ferretti, Alexandre Bellier, Julien Ghelfi

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In one paragraph

Article in Cardiovascular and interventional radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Improving Standards for Embolization of Adhesive Capsulitis.Cardiovascular and interventional radiology · 2026
    Review
  4. Imipenem/Cilastatin in Embolization: From Antibiotic to Therapeutic Agent.Cardiovascular and interventional radiology · 2025
    Review
  5. Article
  6. Clinical Outcomes of Shoulder Artery Embolization for Adhesive Capsulitis.Cardiovascular and interventional radiology · 2025
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mathieu FinasUniversity of Grenoble-Alpes, Grenoble, France.
Julien FrandonDepartment of Radiology, Nimes University Hospital, Nimes, France.
Emeric GremenUniversity of Grenoble-Alpes, Grenoble, France.
Clément HorteurUniversity of Grenoble-Alpes, Grenoble, France.
Michaël BenassayagDepartment of Orthopaedic Surgery, Medipôle de Savoie Hospital, Challes-les-Eaux, France.
Gabriel LateurDepartment of Orthopaedic Surgery Department, Albertville Hospital, Albertville, France.
Régis PailheUniversity of Grenoble-Alpes, Grenoble, France.
Gilbert FerrettiUniversity of Grenoble-Alpes, Grenoble, France.
Alexandre BellierUniversity of Grenoble-Alpes, Grenoble, France.
Julien GhelfiUniversity of Grenoble-Alpes, Grenoble, France. jghelfi@chu-grenoble.fr.ORCID http://orcid.org/0000-0002-9039-6488
Université Grenoble Alpes · FRCentre National de la Recherche Scientifique · FRUniversité de Nîmes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the efficacy of embolization with imipenem/cilastatin and microspheres in chronic shoulder pain.

methodsThis retrospective study included 29 patients who underwent embolization for chronic shoulder pain between June 2017 and March 2022 with calibrated MSs from 100 to 250 µm or IMP/CS. The main objective was the clinical success evaluated by the Minimum Clinically Important Difference (MCID) at 3 months after the procedure, validated if the patient responded yes to 2 questions: (1) Is the pain less severe than before the procedure? (2) Are you satisfied with the procedure? The decrease in visual analogue pain scale scores and the safety of the procedure were evaluated.

resultsEmbolization was achieved in all patients. In the MS group, 4/15 patients (26.7%) experienced clinical success at 3 months according to MCID versus 10/14 patients (71.4%) in the IMP/CS group (p = 0.02). The mean VAS decreases were respectively  - 28.6% ± 34.6 in the MS group and  - 36.8% ± 27.8 in the IMP/CS group at 1 month (p = 0.50), - 29.9% ± 29.0 and - 39.6% ± 23.0 at 3 months (p = 0.33) and - 30.6% ± 32.8 and - 46.6% ± 28.4 at 6 months after the procedure (p = 0.26). Eleven patients (73.3%) in the MS group and 3 patients (21.4%) in the IMP/CS group had complications (p = 0.01). Among them, 2/15 patients (13.3%) had transient skin ischaemia in the MS group.

conclusionEmbolization with IMP/CS may be more effective and safer than MSs in the management of chronic shoulder pain.

Indexed as

CilastatinImipenemCilastatin, Imipenem Drug CombinationDrug CombinationsHumansMicrospheresRetrospective StudiesShoulder PainTreatment OutcomeCilastatinCilastatin, Imipenem Drug CombinationDrug CombinationsImipenemChronic shoulder painCilastatinEmbolizationImipenemNeovesselsSafety

Identifiers

PMID36826491
OpenAlexW4321749463

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.