SynthesisWorld journal of surgery2023
General Anesthesia Versus Regional Anesthesia in the Elderly Patients Undergoing Hip Fracture Surgeries: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.
Synthesis in World journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Regional versus general anesthesia for femur and hip fracture surgery: A meta-analysis of postoperative outcomes and complications.The Journal of international medical research · 2026Pooled it
- Comparing perioperative outcomes between regional anesthesia and general anesthesia in patients undergoing hip fracture surgery: a systematic review and meta-analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Pooled it
- Human Umbilical Cord-Derived Mesenchymal Stem Cells-Involved Strategies: Advancing Tendon Injuries Therapy Towards Clinical Translation.Stem cell reviews and reports · 2026Review
- Myocardial Injury During the Immediate Postoperative Period After Endovascular Aortic Repair: A Prospective Observational Study.Bioengineering (Basel, Switzerland) · 2026Article
- NT-proBNP With Postoperative Complications and 2-Year Mortality Among Hip Fracture Patients: An Observational Cohort Study.Orthopaedic surgery · 2026Observational
- Effects of General Anesthesia Versus Spinal Anesthesia on Early Postoperative Cognition and 30-Day Activities of Daily Living in Elderly Hip Fracture Patients in a Chinese Plateau Region.International journal of general medicine · 2026Article
- Comparative Outcomes of Surgical Interventions for Femoral Neck Fractures: A Multicenter Analysis and Review of the Literature.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- Postoperative delirium in orthopedic patients - identifying contributing factors and therapeutic strategies: A review.Medicine · 2025Review
- Comparison of Cerebral Blood Flow During General Anesthesia in Elderly Patients with and Without Dementia: A Prospective Controlled Clinical Trial.Journal of clinical medicine · 2025Article
- One-Year Functional Outcomes Following Geriatric Hip Fracture: A Prospective Cohort Analysis.Orthopaedic surgery · 2025Article
- From Pain Control to Early Mobility: The Evolution of Regional Anesthesia in Geriatric Total Hip Arthroplasty.Reports (MDPI) · 2025Review
- Epidemiology and factors associated with the perioperative course of patients undergoing hip fracture during the initial phase of the state of emergency declared in 2020.Frontiers in medicine · 2025Article
- The Influence of Regional Anesthesia on the Systemic Stress Response.Reports (MDPI) · 2024Review
- Anesthesia's Influence on Postoperative In-Hospital Morbidity-Mortality in Proximal Femoral Fractures in the Elderly.Medicina (Kaunas, Lithuania) · 2024Article
- Evaluation and Prevention of Perioperative Respiratory Failure.Journal of clinical medicine · 2024Review
- Comparison of three different internal fixation methods in the treatment of femoral neck fracture.Heliyon · 2024Article
- General versus spinal anesthesia: are we asking the right question?Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Article
- Patients risk for mortality at 90 days after proximal femur fracture - a retrospective study in a tertiary care hospital.BMC geriatrics · 2024Article
- Correlation Between Anesthesia Methods and Adverse Short-Term Postoperative Outcomes Depending on Frailty: A Prospective Cohort Study.Clinical interventions in aging · 2024Observational
- The potential risk factors of postoperative cognitive dysfunction for endovascular therapy in acute ischemic stroke with general anesthesia.Open medicine (Warsaw, Poland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgery is the preferred treatment option for the elderly patients with hip fractures. However, the choice of general anesthesia (GA) or regional anesthesia (RA) remains controversial. The quality of evidence has further improved with the advent of several high-quality randomized clinical trials (RCTs) in the last two years. The purpose of this study was to compare the clinical outcomes of two anesthetic techniques in elderly patients undergoing hip fracture surgeries.
methodsEligible studies were identified from PubMed/MEDLINE, Web of Science, Scopus, EMBASE and reference lists from January 2000 to June 2022 in this current systematic review and meta-analysis. The outcomes included the surgery-related outcomes (duration of surgery, duration of anesthesia, intraoperative blood loss and number of transfusions) and postoperative outcomes (30-day mortality, postoperative delirium,cardiovascular events and other complications).
resultsA total of 10 RCTs were included, and a total of 3594 patients were analyzed. RA was associated with shorter duration of surgery, shorter length of hospital stays and less intraoperative blood loss compared to GA. There were no significant differences between the two groups in the number of blood transfusions, duration of anesthesia, 30-day mortality or postoperative delirium.
conclusionsOur pooled analysis identified no significant differences in terms of the safety between RA and GA, while RA reduces intraoperative blood loss, length of hospital stays and duration of surgery. These results suggest that RA appears to be preferable for the elderly patients with hip fractures.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.