Evidence map›Paper›PMID 36826348›Full record

ArticleInfectious disease reports2023

Long-Term Survivors in a Cohort of People Living with HIV Diagnosed between 1985 and 1994: Predictive Factors Associated with More Than 25 Years of Survival.

Federica Cosentino, Andrea Marino, Laura Anile, Vittoria Moscatt, Maria Gussio, Vincenzo Boscia, Roberto Bruno, Giuseppe Nunnari, Alfredo Pulvirenti, Grete Francesca Privitera and 3 more

Open access · goldAbstract read
In one paragraph

Article in Infectious disease reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Federica CosentinoUnit of Infectious Diseases, Department of Clinical and Experimental Medicine, University of Messina, 98124 Messina, Italy.
Andrea MarinoUnit of Infectious Diseases, "Garibaldi" Hospital, 95122 Catania, Italy.ORCID 0000-0002-5650-6911
Laura AnileUnit of Pediatrics, Department of Medical and Surgical Sciences, "Alma Mater" University of Bologna, 40126 Bologna, Italy.
Vittoria MoscattUnit of Infectious Diseases, Department of Clinical and Experimental Medicine, University of Messina, 98124 Messina, Italy.
Maria GussioUnit of Infectious Diseases, "Garibaldi" Hospital, 95122 Catania, Italy.
Vincenzo BosciaUnit of Infectious Diseases, "Garibaldi" Hospital, 95122 Catania, Italy.
Roberto BrunoUnit of Infectious Diseases, "Garibaldi" Hospital, 95122 Catania, Italy.
Giuseppe NunnariUnit of Infectious Diseases, Department of Clinical and Experimental Medicine, University of Messina, 98124 Messina, Italy.ORCID 0000-0002-8113-8452
Alfredo PulvirentiUnit of Informatics, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Grete Francesca PriviteraUnit of Informatics, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-1807-4780
Bruno Santi CacopardoUnit of Infectious Diseases, "Garibaldi" Hospital, 95122 Catania, Italy.
Manuela CeccarelliUnit of Infectious Diseases, "Garibaldi" Hospital, 95122 Catania, Italy.ORCID 0000-0001-5987-3576
Benedetto Maurizio CelesiaUnit of Infectious Diseases, "Garibaldi" Hospital, 95122 Catania, Italy.ORCID 0000-0002-6919-1955
University of Catania · ITUniversity of Messina · ITOspedale Garibaldi · ITUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the mortality rate among individuals diagnosed during the pre-Highly Active Antiretroviral Treatment era has been substantial, a considerable number of them survived. Our study aimed to evaluate the prevalence of HIV long-term survivors in a cohort of People Living with HIV diagnosed between 1985 and 1994 and to speculate about potential predictive factors associated to long survival. This is a retrospective single-center study. Subjects surviving more than 300 months (25 years) from HIV diagnosis were defined as Long Term Survivors. Overall, 210 subjects were enrolled. More than 75.24% of the included people living with HIV were males, with a median age of 28 years (IQR 25-34). The prevalent risk factors for HIV infection were injection drug use (47.62%), followed by unprotected sex among heterosexual individuals (23.81%). Ninety-three individuals (44.29%) could be defined as LTS with a median (IQR) survival of 333 (312-377) months. A hazard ratio of 12.45 (95% CI 7.91-19.59) was found between individuals who were exposed to Highly Active AntiRetroviral Treatment (HAART) and individuals who were not, with the latter being at greater risk of death. The availability and accessibility of effective antiretroviral therapy for people living with HIV remain the cornerstone of survival.

Indexed as

HAARTHIV epidemiologylong-term survivors

Identifiers

PMID36826348
PMCPMC9957088
OpenAlexW4317746147

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.