ReviewGels (Basel, Switzerland)2023
Chitosan and Pectin Hydrogels for Tissue Engineering and In Vitro Modeling.
Review in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Mimicking tumor hypoxia in a glioblastoma-on-a-chip.Materials today. Bio · 2026Article
- Biomimetic Scaffold-Based 3D Models for Decoding Cancer Biology and Advancing Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Intrinsically Thermoresponsive Hydrogels from Molecularly Engineered Chitosan.Gels (Basel, Switzerland) · 2026Article
- Harnessing Polymeric Xerogels for Enhanced Wound Care: Properties, Mechanisms, and Applications.ACS materials Au · 2026Review
- Chitosan stimulates root hair callose deposition, endomembrane dynamics, and inhibits root hair growth.Plant, cell & environment · 2025Article
- Hydrogels and nanogels: effectiveness in dermal applications.Beilstein journal of nanotechnology · 2025Review
- A Review of Chitosan-Based Materials for Biomedical, Food, and Water Treatment Applications.Materials (Basel, Switzerland) · 2024Review
- Hydrogels Based on Polyacrylamide and Pectin Containing Rice Husk Ash: Preparation, Characterization and Application in Formulation of Cementitious Materials.Materials (Basel, Switzerland) · 2024Article
- Article
- Natural Regenerative Hydrogels for Wound Healing.Gels (Basel, Switzerland) · 2024Review
- Swelling, Protein Adsorption, and Biocompatibility of Pectin-Chitosan Hydrogels.Gels (Basel, Switzerland) · 2024Article
- Harnessing extracellular vesicles-mediated signaling for enhanced bone regeneration: novel insights into scaffold design.Biomedical materials (Bristol, England) · 2024Article
- The Evolution of Technology-Driven In Vitro Models for Neurodegenerative Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Insights into Translational and Biomedical Applications of Hydrogels as Versatile Drug Delivery Systems.AAPS PharmSciTech · 2024Review
- The biological applications of IPN hydrogels.ADMET & DMPK · 2024Review
- Recent Advances in Micro- and Nano-Drug Delivery Systems Based on Natural and Synthetic Biomaterials.Polymers · 2023Review
- New Quaternary Ammonium Derivatives Based on Citrus Pectin.Polymers · 2023Article
- Chitosan/Virgin-Coconut-Oil-Based System Enriched with Cubosomes: A 3D Drug-Delivery Approach.Marine drugs · 2023Article
- Effect of Chitosan on Rheological, Mechanical, and Adhesive Properties of Pectin-Calcium Gel.Marine drugs · 2023Article
- In Vitro and In Vivo Biocompatibility Assessment of a Thermosensitive Injectable Chitosan-Based Hydrogel for Musculoskeletal Tissue Engineering.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogels are fascinating biomaterials that can act as a support for cells, i.e., a scaffold, in which they can organize themselves spatially in a similar way to what occurs in vivo. Hydrogel use is therefore essential for the development of 3D systems and allows to recreate the cellular microenvironment in physiological and pathological conditions. This makes them ideal candidates for biological tissue analogues for application in the field of both tissue engineering and 3D in vitro models, as they have the ability to closely mimic the extracellular matrix (ECM) of a specific organ or tissue. Polysaccharide-based hydrogels, because of their remarkable biocompatibility related to their polymeric constituents, have the ability to interact beneficially with the cellular components. Although the growing interest in the use of polysaccharide-based hydrogels in the biomedical field is evidenced by a conspicuous number of reviews on the topic, none of them have focused on the combined use of two important polysaccharides, chitosan and pectin. Therefore, the present review will discuss the biomedical applications of polysaccharide-based hydrogels containing the two aforementioned natural polymers, chitosan and pectin, in the fields of tissue engineering and 3D in vitro modeling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.