Evidence map›Paper›PMID 36826295›Full record

ArticleGels (Basel, Switzerland)2023

Efficacy of 5% Aminolaevulinic Acid and Red Light on

Teocrito Carlesi, Tatiane Cristina Dotta, Tania Vanessa Pierfelice, Emira D'Amico, Stefania Lepore, Domenico Tripodi, Adriano Piattelli, Simonetta D'Ercole, Morena Petrini

Open access · goldAbstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Assessment of photodynamic therapy efficacy againstJournal of biomedical optics · 2025
    Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Teocrito CarlesiDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.
Tatiane Cristina DottaDepartment of Dental Materials and Prosthodontics, School of Dentistry of Ribeirão Preto, University of São Paulo, Sao Paulo 14040-904, Brazil.ORCID 0000-0001-6376-679X
Tania Vanessa PierfeliceDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-5886-2186
Emira D'AmicoDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0003-2414-7130
Stefania LeporeDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.
Domenico TripodiDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.
Adriano PiattelliSchool of Dentistry, Saint Camillus International University for Health Sciences (Unicamillus), 00131 Rome, Italy.
Simonetta D'ErcoleDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-4797-4019
Morena PetriniDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.
University of Chieti-Pescara · ITSaint Camillus International University of Health and Medical Sciences · ITUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this ex vivo study, the aim was to evaluate the effects of ALAD and red light on

methodsA total of 70 extracted, single-rooted teeth were used. The teeth were decoronated at the length of the roots to approximately 15 mm and then instrumented. The apical foramen was sealed by composite resin, and the root canals were infected with a pure culture of

resultsThe best treatment is obtained with 2.5% NaOCl. Except for ALAD + red light vs. 1% NaOCl, a statistically significant difference is recorded for all treatments. The combination of 2.5% NaOCl and ALAD + 7 min irradiation produces an evident killing effect on the

conclusionsThis ex vivo study shows that ALAD gel with light irradiation is an efficacious protocol that exerts a potent antibacterial activity against

Indexed as

5-aminolevulinic acidendodonticsEnterococcus faecalisphotodynamic therapyred light

Identifiers

PMID36826295
PMCPMC9957220
OpenAlexW4319083926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.