Evidence map›Paper›PMID 36826278›Full record

ArticleGels (Basel, Switzerland)2023

Antimicrobial Efficacy Assessment and Rheological Investigation of Two Different Hand Sanitizers Compared with the Standard Reference WHO Formulation 1.

Sabrina Sommatis, Maria Chiara Capillo, Cristina Maccario, Raffaele Rauso, Edoardo D'Este, Martha Herrera, Mauro Castiglioni, Roberto Mocchi, Nicola Zerbinati

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sabrina SommatisUB-CARE S.r.l. Spin-Off, University of Pavia, 27010 Prado, Italy.
Maria Chiara CapilloUB-CARE S.r.l. Spin-Off, University of Pavia, 27010 Prado, Italy.ORCID 0000-0003-0459-155X
Cristina MaccarioUB-CARE S.r.l. Spin-Off, University of Pavia, 27010 Prado, Italy.
Raffaele RausoHead and Neck Unit, Clinica Cobellis, 84078 Vallo della Lucania, Italy.ORCID 0000-0002-4497-3563
Edoardo D'EsteCentro Medico Polispecialistico, 27100 Pavia, Italy.
Martha HerreraCentro Avanzado de Dermatologia y Laser, San Pedro Sula 21101, Honduras.
Mauro CastiglioniLem Compounding Research S.r.l., 20823 Lentate sul Seveso, Italy.
Roberto MocchiUB-CARE S.r.l. Spin-Off, University of Pavia, 27010 Prado, Italy.
Nicola ZerbinatiDepartment of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: recently, the use of alcohol-based hand sanitizers (ABHSs) has become very frequent, and an evaluation of the stability and effectiveness of their formulations is a critical topic which should be carefully considered. (2) Methods: starting from the characterization of the hand sanitizers object of the study, our interest was focused on their rheological behavior in order to confirm their intrinsic features, but also the stability of each formulation in different conditions of shear and temperature; the second aspect concerns the antimicrobial assessment through a panel of in vitro and in vivo experimental trials. (3) Results: rheological investigation confirmed good stability for the two hand sanitizers in gel formula with respect to the reference in liquid formula; the antimicrobial activity evaluation showed good efficacy of each formulation both in vitro and in vivo. (4) Conclusions: altogether, our overview presents a valid quality control assessment to ensure the stability and efficacy of an alcohol-based hand sanitizer.

Indexed as

ABHSagar diffusion testalcohol-based hand sanitizerantimicrobial activityin vitroin vivoMBCMICorganoleptic featuresrheology

Identifiers

PMID36826278
PMCPMC9957052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.