Evidence map›Paper›PMID 36826171›Full record

ReviewClinics and practice2023

Notalgia Paresthetica Review: Update on Presentation, Pathophysiology, and Treatment.

Christopher Robinson, Evan Downs, Yanet De la Caridad Gomez, Chinonso Nduaguba, Parker Woolley, Giustino Varrassi, Jatinder Gill, Thomas T Simopoulos, Omar Viswanath, Cyrus A Yazdi

Open access · goldAbstract readReview
In one paragraph

Review in Clinics and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. A systematic review of procedural modalities in the treatment of notalgia paresthetica.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Neural therapy in notalgia paresthetica.Archives of dermatological research · 2024
    Article
  7. Acta dermato-venereologica · 2024
    Article
  8. Thyroid Malignancy and Cutaneous Lichen Amyloidosis: Key Points AmidInternational journal of molecular sciences · 2024
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Christopher RobinsonBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA 02215, USA.
Evan DownsSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.
Yanet De la Caridad GomezPain Management Center, Harvard Medical School, Boston, MA 02215, USA.ORCID 0000-0001-6845-4138
Chinonso NduagubaBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA 02215, USA.
Parker WoolleyBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA 02215, USA.
Giustino VarrassiPaolo Procacci Foundation, 00193 Roma, Italy.ORCID 0000-0002-3822-2923
Jatinder GillBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA 02215, USA.
Thomas T SimopoulosBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA 02215, USA.
Omar ViswanathSchool of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA 71103, USA.
Cyrus A YazdiBeth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care and Pain Medicine, Harvard Medical School, Boston, MA 02215, USA.
Beth Israel Deaconess Medical Center · USCreighton University · USFondazione Roma · ITHarvard University · USLouisiana State University Health Sciences Center Shreveport · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewNotalgia paresthetica (NP) is a chronic cutaneous neuropathy primarily characterized by localized pruritus and associated dysesthesias, including sensations of pain, numbness, and tingling. The sensory neuropathy characteristic of NP is thought to result from spinal nerve entrapment caused by degenerative changes in the spine or musculoskeletal compression. This review summarizes the current medical literature with a focus on the past five years regarding NP, its pathophysiology, presentation, and current treatment options. RECENT

findingsThough treatments exist with varying efficacy, to date, there exists no definitive treatment for NP. Treatment options for NP are varied and range from topical and oral agents to interventional procedures and physical therapy. Of the treatments evaluated, topical capsaicin remains the most efficacious treatment for NP.

conclusionsThe lack of established treatment guidelines makes treating NP complicated as it dramatically affects patients' quality of life. Further research with larger sample sizes is needed to evaluate better the most effective treatment and dosing regimen for patients afflicted with NP.

Indexed as

capsaicincutaneous neuropathynostalgia parestheticatopical treatments

Identifiers

PMID36826171
PMCPMC9955802
OpenAlexW4321371162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.