Evidence map›Paper›PMID 36826159›Full record

ArticleClinics and practice2023

Which Patients with Chronic Periprosthetic Joint Infection Are Less Suitable to Successful Two Stage Exchange Arthroplasty Surgery? A Retrospective Clinical Trial.

Alberto Di Martino, Gabriele Di Carlo, Davide Pederiva, Valentino Rossomando, Federico Pilla, Matteo Brunello, Claudio D'Agostino, Leonardo Tassinari, Eleonora Zamparini, Cesare Faldini

Open access · goldAbstract read
In one paragraph

Article in Clinics and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Alberto Di MartinoIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.ORCID 0000-0002-0716-4951
Gabriele Di CarloIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.ORCID 0000-0002-8846-0655
Davide PederivaIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.ORCID 0000-0003-3657-8923
Valentino RossomandoIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.ORCID 0000-0002-3153-8693
Federico PillaIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.
Matteo BrunelloIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.ORCID 0000-0001-9376-5480
Claudio D'AgostinoIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.ORCID 0000-0003-2616-0662
Leonardo TassinariIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.ORCID 0000-0003-3834-6798
Eleonora ZampariniInfectious Diseases Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna-Policlinico di Sant'Orsola, 40138 Bologna, Italy.
Cesare FaldiniIst Orthopaedic Department, IRCCS-Istituto Ortopedico Rizzoli, via Giulio Cesare Pupilli 1, 40136 Bologna, Italy.
Istituto Ortopedico Rizzoli · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTwo-stage exchange (TSE) arthroplasty is currently considered the gold standard for chronic periprosthetic joint infections (PJIs), despite a failure rate reported in up to 10% of patients. Little is known about the risk factors that may compromise successful TSE arthroplasty management in such patients. The main purpose of the current study was to highlight the potential risk factors of patients with chronic PJIs after THA managed by implant removal, outlining the differences between reimplanted patients and those that were never reimplanted because of a non-eradicated infection.

methodsWe conducted a retrospective observational study of patient candidates for TSE arthroplasty surgery, managed at the authors' institution, over a four-year timeframe. The data were retrieved from the hospital's information database. The enrolled population was divided into two Groups: A, reimplanted; B, non-reimplanted because of a non-eradicated infection within one year. For each Group, demographic information, PJI-related risk factors, type of pathogen and presence of single or polymicrobial infection, were collected and analyzed.

resultsIn total, 21 patients were included in the study, 14 patients in Group A and 7 in Group B. Major Depression (

conclusionsPatients with major depression, or those hosting polymicrobial periprosthetic hip infections, are more susceptible to failure of TSE arthroplasty procedures for chronic PJIs, hampering THA reimplantation. Current findings may drive further research and contribute to the understanding of the role of these risk factors in chronic PJI patients.

Indexed as

chronic periprosthetic hip infectiondepressionpolymicrobial PJItwo-stage exchange failure

Identifiers

PMID36826159
PMCPMC9954882
OpenAlexW4318485990

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.