Evidence map›Paper›PMID 36826101›Full record

ArticleCurrent oncology (Toronto, Ont.)2023

Diagnostic Performance of Screening Tools for Depressive Symptoms in Vulnerable Older Patients with Cancer Undergoing Comprehensive Geriatric Assessment (CGA): Results from the SCREEN Pilot Study.

Laura Tack, Ann-Sophie Maenhoudt, Lore Ketelaars, Jolien De Zutter, Stefanie Pinson, Laura Keunebrock, Lorenz Haaker, Kathleen Deckmyn, Mathilde Gheysen, Cindy Kenis and 8 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 2 countries.

Laura TackDepartment of Medical Oncology, OECI-designated Kortrijk Cancer Centre, General Hospital Groeninge, 8500 Kortrijk, Belgium.ORCID 0000-0002-7851-4285
Ann-Sophie MaenhoudtDepartment of Psychology, General Hospital Groeninge, 8500 Kortrijk, Belgium.
Lore KetelaarsDepartment of Psychology, General Hospital Groeninge, 8500 Kortrijk, Belgium.
Jolien De ZutterDepartment of Psychology, General Hospital Groeninge, 8500 Kortrijk, Belgium.
Stefanie PinsonDepartment of Psychology, General Hospital Groeninge, 8500 Kortrijk, Belgium.
Laura KeunebrockDepartment of Psychology, General Hospital Groeninge, 8500 Kortrijk, Belgium.
Lorenz HaakerDepartment of Medical Oncology, OECI-designated Kortrijk Cancer Centre, General Hospital Groeninge, 8500 Kortrijk, Belgium.ORCID 0000-0002-4707-7641
Kathleen DeckmynDepartment of Medical Oncology, OECI-designated Kortrijk Cancer Centre, General Hospital Groeninge, 8500 Kortrijk, Belgium.
Mathilde GheysenDepartment of Medical Oncology, OECI-designated Kortrijk Cancer Centre, General Hospital Groeninge, 8500 Kortrijk, Belgium.
Cindy KenisDepartment of General Medical Oncology, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-7932-6817
Hans WildiersDepartment of General Medical Oncology, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-8990-7837
Laurence DepoorterDepartment of Geriatrics, General Hospital Groeninge, 8500 Kortrijk, Belgium.
Pieter-Jan GeertsDepartment of Psychiatry, General Hospital Groeninge, 8500 Kortrijk, Belgium.ORCID 0000-0003-1002-2695
Rebecca ChandlerSchool of Allied Health, Faculty of Health, Education, Medicine and Social Care, Chelmsford CM1 1SQ, UK.
Tom BoterbergDepartment of Human Structure and Repair, Ghent University, 9000 Ghent, Belgium.
Patricia SchofieldSchool of Nursing and Midwifery, Faculty of Health, University of Plymouth, Plymouth PL4 8AA, UK.ORCID 0000-0003-4242-754X
Christopher N ParrisMedical Technology Research Centre (MTRC), School of Life Sciences, Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK.
Philip R DebruyneDepartment of Medical Oncology, OECI-designated Kortrijk Cancer Centre, General Hospital Groeninge, 8500 Kortrijk, Belgium.ORCID 0000-0001-5438-9697
AZ Groeninge · BEKU Leuven · BEAnglia Ruskin University · GBGhent University · BEUniversity of Plymouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a common and disabling disorder in later life, particularly among people with poor physical health. There are many screening tools available that can be used to examine depressive symptoms; however, not all of them may be appropriate or accurate for older adults with cancer. This pilot study was designed to test the diagnostic performance of two screening tools and their short versions in a cohort of vulnerable (G8 score ≤ 14/17) older patients with cancer undergoing comprehensive geriatric assessment (CGA). The prospective analysis covered 50 vulnerable patients with cancer aged ≥70 years. The diagnostic performance of the Geriatric Depression Scale (GDS)-15, GDS-4, Patient Health Questionnaire (PHQ)-9 and PHQ-2 was compared to the 'gold standard' Structured Clinical Interview for DSM-5 Disorders (SCID-5-S) depression module A. The sensitivity and specificity in detecting depressive symptoms were the highest in the case of PHQ-2, with an area under the receiver operating characteristic curve (AUROC) of 92.7%. The AUROC for the 9-item version, PHQ-9, was 90.2%. For the GDS-15 and GDS-4, the AUROC was only 56.2% and 62.0%, respectively. The SCREEN pilot study illustrates the potential benefit of using a shorter screening tool, PHQ-2, to identify older patients with cancer who would benefit from a more in-depth emotional evaluation as part of a CGA.

Indexed as

DepressionNeoplasmsAgedEarly Detection of CancerGeriatric AssessmentHumansPilot ProjectsdepressionGeriatric Depression Scaleolder adults with canceroncogeriatricPatient Health Questionnaire

Identifiers

PMID36826101
PMCPMC9955591
OpenAlexW4319003563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.