Evidence map›Paper›PMID 36826070›Full record

ReviewCurrent oncology (Toronto, Ont.)2023

Pilomatrix Carcinoma: Report of Two Cases of the Head and Review of the Literature.

Ludovica Toffoli, Giulia Bazzacco, Claudio Conforti, Claudio Guarneri, Roberta Giuffrida, Enrico Zelin, Nicola di Meo, Iris Zalaudek

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. A case of pilomatrix carcinoma found in the shoulder.Journal of surgical case reports · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ludovica ToffoliDermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
Giulia BazzaccoDermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.ORCID 0000-0001-8135-7025
Claudio ConfortiDermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.ORCID 0000-0001-5126-8873
Claudio GuarneriDepartment of Biomedical and Dental Sciences and Morpho Functional Imaging, University of Messina, 98124 Messina, Italy.ORCID 0000-0003-3918-8779
Roberta GiuffridaDepartment of Clinical and Experimental Medicine, Dermatology, University of Messina, 98124 Messina, Italy.
Enrico ZelinDermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.ORCID 0000-0001-9276-3627
Nicola di MeoDermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
Iris ZalaudekDermatology Clinic of Trieste, Maggiore Hospital, University of Trieste, 34100 Trieste, Italy.
University of Trieste · ITUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPilomatrix carcinoma (PC) is a rare skin tumor arising from hair follicle matrix cells. It is locally aggressive with a high rate of local recurrence after surgical excision. Few cases in the literature have been described and the management is not well defined.

objectivesThe aim of this study was to present two cases of PC located on the head and review the relevant literature about epidemiology, clinical and dermoscopic evaluation, characteristics of local and distant metastases, local recurrence rate and management of this rare skin tumor.

methodsWe consulted databases from PubMed, Research Gate and Google Scholar, from January 2012 to November 2022. We reviewed the literature and reported two additional cases.

resultsWe selected 52 tumors in middle-aged to older patients located mostly on the head. Dermoscopy evaluation was rarely performed in the pre-operative diagnostic setting. The most definitive treatment was wide local excision, but local recurrences were common. In total, we observed 11 cases of recurrences and 9 patients with locoregional or distant metastases. Four patients received adjuvant radiotherapy, two patients needed chemotherapy and local cancer therapy and one patient received radiochemotherapy.

conclusionOur reports and the review of the literature can provide a better awareness and management of this rare tumor.

Indexed as

Bone NeoplasmsCarcinomaHair DiseasesSkin NeoplasmsFemaleHumansMiddle Agedcarcinomadermoscopyhistopathologypilomatrixtherapy

Identifiers

PMID36826070
PMCPMC9955132
OpenAlexW4317622553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.