Evidence map›Paper›PMID 36826007›Full record

ArticleCurrent issues in molecular biology2023

Clinical Investigation of Leukocyte DNA Damage in COVID-19 Patients.

Hasan Doğan, Aslı Kara, Erdem Çankaya, Eda Balkan, Muhammet Ali Gürbüz, Murat Kızılkaya, Merve Aykaç

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hasan DoğanDepartment of Medical Biology, Faculty of Medicine, Ataturk University, Erzurum 25240, Turkey.ORCID 0000-0002-5232-4336
Aslı KaraDepartment of Internal Medicine, Erzurum Regional Training and Research Hospital, Health Sciences University, Erzurum 25100, Turkey.
Erdem ÇankayaDepartment of Nephrology, Faculty of Medicine, Ataturk University, Erzurum 25240, Turkey.ORCID 0000-0003-3971-3318
Eda BalkanDepartment of Medical Biology, Faculty of Medicine, Ataturk University, Erzurum 25240, Turkey.
Muhammet Ali GürbüzDepartment of Histology and Embryology, Faculty of Medicine, Ataturk University, Erzurum 25240, Turkey.
Murat KızılkayaDepartment of Medical Biology, Faculty of Medicine, Ataturk University, Erzurum 25240, Turkey.
Merve AykaçDepartment of Medical Biology, Faculty of Medicine, Ataturk University, Erzurum 25240, Turkey.
Atatürk University · TRErzurum Regional Training and Research Hospital · TR

Funding

Atatürk University TSA-2021-8869
6 · The paper itself

Abstract

This prospective cross-sectional study aimed to evaluate leukocyte DNA damage in coronavirus disease (COVID-19) patients. In this study, 50 COVID-19-positive patients attending the Erzurum City Hospital Internal Medicine Outpatient Clinic and 42 control group patients were included. DNA damage was detected in living cells through leukocyte isolation in 50 COVID-19-positive patients using the comet assay method. DNA tail/head (olive) moments were evaluated and compared. White blood cells (WBC), red blood cells (RBC), hemoglobin (HGB), neutrophils (NEU), lymphocytes (LYM), eosinophils (EO), monocytes (MONO), basophils (BASO), platelets (PLT), and the neutrophil/lymphocyte ratio (NLR) were analyzed. The RBC, lymphocyte, eosinophil, and monocyte means were significantly higher in the control group (

Indexed as

comet assayCOVID-19DNA damagelymphocytelymphopenianeutrophil/lymphocyte ratio (NLR)

Identifiers

PMID36826007
PMCPMC9955698
OpenAlexW4317622337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.