ReviewCurrent issues in molecular biology2023
Applications and Prospects of CRISPR/Cas9-Mediated Base Editing in Plant Breeding.
Review in Current issues in molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Advances in CRISPR Base Editing: From Molecular Evolution to Therapeutic Applications in Genomic Medicine.Journal of cellular and molecular medicine · 2026Review
- Application of compact CRISPR/Cas nucleases for citrus genome editing.Transgenic research · 2026Article
- Beyond Cutting: CRISPR-Driven Synthetic Biology Toolkit for Next-Generation Microalgal Metabolic Engineering.International journal of molecular sciences · 2025Review
- Review
- Breeding herbicide-resistant rice using CRISPR-Cas gene editing and other technologies.Plant communications · 2025Review
- Emerging applications of gene editing technologies for the development of climate-resilient crops.Frontiers in genome editing · 2025Review
- Functional Genomics and Comparative Genomics Analysis in Plants.Current issues in molecular biology · 2024Article
- CRISPR/Cas system-mediated base editing in crops: recent developments and future prospects.Plant cell reports · 2024Review
- Advances in understanding the graft healing mechanism: a review of factors and regulatory pathways.Horticulture research · 2024Article
- Investigation of Imidazolinone Herbicide Resistance Gene with KASP Markers forPlants (Basel, Switzerland) · 2024Article
- Glutaredoxin in Rice Growth, Development, and Stress Resistance: Mechanisms and Research Advances.International journal of molecular sciences · 2023Review
- The Microbial Connection to Sustainable Agriculture.Plants (Basel, Switzerland) · 2023Review
- Genome editing for healthy crops: traits, tools and impacts.Frontiers in plant science · 2023Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein 9 system (Cas9) has been used at length to optimize multiple aspects of germplasm resources. However, large-scale genomic research has indicated that novel variations in crop plants are attributed to single-nucleotide polymorphisms (SNPs). Therefore, substituting single bases into a plant genome may produce desirable traits. Gene editing by CRISPR/Cas9 techniques frequently results in insertions-deletions (indels). Base editing allows precise single-nucleotide changes in the genome in the absence of double-strand breaks (DSBs) and donor repair templates (DRTs). Therefore, BEs have provided a new way of thinking about genome editing, and base editing techniques are currently being utilized to edit the genomes of many different organisms. As traditional breeding techniques and modern molecular breeding technologies complement each other, various genome editing technologies have emerged. How to realize the greater potential of BE applications is the question we need to consider. Here, we explain various base editings such as CBEs, ABEs, and CGBEs. In addition, the latest applications of base editing technologies in agriculture are summarized, including crop yield, quality, disease, and herbicide resistance. Finally, the challenges and future prospects of base editing technologies are presented. The aim is to provide a comprehensive overview of the application of BE in crop breeding to further improve BE and make the most of its value.
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Registered trials
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