Evidence map›Paper›PMID 36825927›Full record

ArticleJournal of materials chemistry. B2023

Interpenetrating network design of bioactive hydrogel coatings with enhanced damage resistance.

Megan Wancura, Abbey Nkansah, Malgorzata Chwatko, Andrew Robinson, Ashauntee Fairley, Elizabeth Cosgriff-Hernandez

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. A computational framework to optimize the mechanical behavior of synthetic vascular grafts.Journal of the mechanical behavior of biomedical materials · 2025
    Article
  4. Design of PEG-Based Hydrogels as Soft Ionic Conductors.Journal of biomedical materials research. Part A · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Megan WancuraDepartment of Chemistry, The University of Texas at Austin, Austin, TX 78712, USA.
Abbey NkansahDepartment of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA. cosgriff.hernandez@utexas.edu.
Malgorzata ChwatkoDepartment of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA. cosgriff.hernandez@utexas.edu.
Andrew RobinsonDepartment of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA. cosgriff.hernandez@utexas.edu.
Ashauntee FairleyDepartment of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA. cosgriff.hernandez@utexas.edu.
Elizabeth Cosgriff-HernandezDepartment of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA. cosgriff.hernandez@utexas.edu.ORCID http://orcid.org/0000-0002-4701-5600

Funding

Injectable Hydrogel Electrodes to Prevent Ventricular ArrhythmiasR01HL162741 · NHLBI · UNIVERSITY OF TEXAS AT AUSTIN · PI Elizabeth Marie Cosgriff-Hernandez, Mehdi Razavi · 2023 to 2026
$2.4M
NHLBI NIH HHS R01 HL162741
6 · The paper itself

Abstract

Bioactive hydrogel coatings offer a promising route to introduce sustained thromboresistance to cardiovascular devices without compromising bulk mechanical properties. Poly(ethylene glycol)-based hydrogels provide antifouling properties to limit acute thromobosis and incorporation of adhesive ligands can be used to promote endothelialization. However, conventional PEG-based hydrogels at stiffnesses that promote cell attachment can be brittle and prone to damage in a surgical setting, limiting their utility in clinical applications. In this work, we developed a durable hydrogel coating using interpenetrating networks of polyether urethane diacrylamide (PEUDAm) and poly(

Indexed as

HydrogelsPolyethylene GlycolsBiocompatible MaterialsCell AdhesionCollagenBiocompatible MaterialsCollagenHydrogelsPolyethylene Glycols

Identifiers

PMID36825927
PMCPMC10682960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.