ArticleRheumatology (Oxford, England)2023
The impact of health literacy: associations with disease activity and medication prescription in patients with rheumatoid arthritis.
Article in Rheumatology (Oxford, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Diversity of health literacy strengths and challenges among migrant patients with inflammatory rheumatic diseases: a qualitative exploration.Rheumatology advances in practice · 2026Article
- Health literacy and control of inflammatory activity in patients with recent-onset rheumatoid arthritis.Rheumatology advances in practice · 2026Article
- Artificial intelligence in patient education: evaluating large language models for understanding rheumatology literature.Frontiers in digital health · 2025Article
- Validation of a new glucocorticoid-specific Patient-Reported Outcome Questionnaire (the Steroid PRO).Annals of the rheumatic diseases · 2024Article
- Health literacy of rheumatology patients in three clinics in Australia and its association with sociodemographic and clinical characteristics.Rheumatology advances in practice · 2024Article
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Abstract
objectiveThe aim of this study was to explore the longitudinal associations between health literacy profiles and disease activity and medication prescription in patients with RA.
methodsPatients with RA who previously completed the Health Literacy Questionnaire (HLQ) and were assigned 1 of 10 distinct health literacy profiles based on cluster analysis were further aggregated into three groups: 'several health literacy limitations', 'some health literacy limitations' and 'good health literacy'. Linear mixed modelling (LMM) was used to analyse the association between health literacy groups and disease activity over the course of 1 year. Chi-squared tests and logistic regression analyses were used to compare medication prescriptions between the groups.
resultsA total of 108 patients with RA were included. LMM showed a significant effect of health literacy group on disease activity over time (P = 0.010). Patients with 'good health literacy' had significantly lower disease activity over time [28-joint DAS with ESR (DAS28-ESR) = 2.4] than patients with 'several health literacy limitations' (DAS28-ESR = 3.1), independent of age, gender and education level. Patients with 'good health literacy' were most often prescribed a biologic DMARD (50%), whereas patients with 'some health literacy limitations' more commonly received a conventional synthetic DMARD only [72.7%; odds ratio (OR) 4.24], and patients with 'several health literacy limitations' were more often prescribed prednisolone (52.4%; OR 3.56).
conclusionSignificant differences in longitudinal disease activity and medication prescription were observed between groups with different health literacy levels. These results stress the importance of insights into the role of health literacy in treatment and outcomes in patients with RA.
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