Evidence map›Paper›PMID 36825581›Full record

ArticleInternational journal of oncology2023

Keratin19 promotes pancreatic cancer progression and poor prognosis via activating the Hedgehog pathway.

Changsheng Zhou, Yi Xiang, Yantao Ren, Ming Li, Xin Gou, Wengang Li

Open access · hybridAbstract read
In one paragraph

Article in International journal of oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Changsheng ZhouSchool of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
Yi XiangDepartment of Hepatobiliary Surgery, Guizhou Provincial People's Hospital, Guiyang, Guizhou 550002, P.R. China.
Yantao RenSchool of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
Ming LiXiamen Medicine Research Institute, Xiamen, Fujian 361005, P.R. China.
Xin GouDepartment of Hepatobiliary Surgery, Guizhou Provincial People's Hospital, Guiyang, Guizhou 550002, P.R. China.
Wengang LiSchool of Medicine, Xiamen University, Xiamen, Fujian 361102, P.R. China.
Xiamen University · CNGuizhou Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is a serious threat to human health, with strong invasiveness, rapid progression and poor prognosis. Tumors expressing keratin 19 (K19) have stronger invasiveness and a worse prognosis. However, the role and mechanism of K19 in pancreatic cancer have remained largely elusive. In the present study, K19 expression was detected in pancreatic cancer tissues, its effect on proliferation, apoptosis and metastasis of pancreatic cancer at the cellular,

Indexed as

Hedgehog ProteinsPancreatic NeoplasmsApoptosisCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansNeoplasm InvasivenessPrognosisHedgehog ProteinsHedgehog pathwaykeratin19pancreatic cancerprognosisprogression

Identifiers

PMID36825581
PMCPMC9946805
OpenAlexW4321459523

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.