Evidence map›Paper›PMID 36825536›Full record

ArticleAIDS research and human retroviruses2023

Herpes Simplex Virus Type 2 Prevalence and Association with Inflammatory Cytokines Among Sexual and Gender Minorities Living With and Without HIV-1 from Lagos, Nigeria.

Meropi Aravantinou, Marlena Plagianos, Afoke Kokogho, Sylvia Adebajo, Rebecca G Nowak, Elizabeth Shoyemi, Charles Ekeh, Kara Lombardi, Sheila A Peel, Stefan D Baral and 5 more

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In one paragraph

Article in AIDS research and human retroviruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 2 countries.

Meropi AravantinouCenter for Biomedical Research, Population Council, New York, New York, USA.
Marlena PlagianosCenter for Biomedical Research, Population Council, New York, New York, USA.
Afoke KokoghoHJF Medical Research International, Abuja, Nigeria.
Sylvia AdebajoCenter for International Health Education and Biosecurity (CIHEB), University of Maryland, Baltimore, Maryland, USA.
Rebecca G NowakInstitute of Human Virology, University of Maryland, Baltimore, Maryland, USA.
Elizabeth ShoyemiPopulation Council Nigeria, Abuja, Nigeria.
Charles EkehPopulation Council Nigeria, Abuja, Nigeria.
Kara LombardiU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Sheila A PeelDiagnostics and Countermeasures Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Stefan D BaralDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
Trevor A CrowellU.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.ORCID 0000-0001-5947-265X
Nina DerbyCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, Washington, USA.
Natalia TeleshovaCenter for Biomedical Research, Population Council, New York, New York, USA.ORCID 0000-0003-3169-4650
Elena MartinelliDepartment of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0002-3416-9627
TRUST/RV368 Study Group
Population Council · USHenry M. Jackson Foundation · USMedical Laboratory Science Council of Nigeria · NGUniversity of Maryland, Baltimore · USInfectious Disease Research Institute · USJohns Hopkins University · USNorthwestern University · USWalter Reed Army Institute of Research · US

Funding

Building TRUSTR01AI120913 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI CHARURAT, MANHATTAN E · 2015 to 2019
$3.3M
TRUSTR01MH099001 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI CHARURAT, MANHATTAN E · 2012 to 2014
$2.9M
Epidemiology Research Training for Public Health Impact in Nigeria (Epi-Nigeria)D43TW010051 · FIC · UNIVERSITY OF MARYLAND BALTIMORE · PI ABIMIKU, ALASH'LE G., CHARURAT, MANHATTAN E · 2016 to 2020
$1.5M
Role of anal microbiota, local cytokines and HIV in persistence of high-risk human papillomavirusK07CA225403 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI NOWAK, REBECCA G. · 2018 to 2022
$677k
HIV immune environment impact on pre-eclampsiaR03AI170156 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MARTINELLI, ELENA · 2022 to 2023
$160k
FIC NIH HHS D43 TW010051NCI NIH HHS K07 CA225403NIAID NIH HHS R01 AI120913NIAID NIH HHS R03 AI170156NIMH NIH HHS R01 MH099001
6 · The paper itself

Abstract

Herpes simplex virus type 2 (HSV-2) is common globally and contributes significantly to the risk of acquiring HIV-1, yet these two sexually transmitted infections have not been sufficiently characterized for sexual and gender minorities (SGM) across Sub-Saharan Africa. To help fill this gap, we performed a retrospective study using plasma and serum samples from 183 SGM enrolled at the Lagos site of the TRUST/RV368 cohort in Nigeria, assayed them for HSV-2 antibodies with the Kalon ELISA and plasma cytokines and chemokines with Luminex, and correlated the findings with HIV-1 viral loads (VLs) and CD4 counts. We found an overall HSV-2 prevalence of 36.6% (49.5% and 23.9% among SGM with and without HIV-1, respectively,

Indexed as

Herpes GenitalisHerpes SimplexHIV-1HIV InfectionsHIV SeropositivitySexual and Gender MinoritiesCytokinesHerpesvirus 2, HumanHumansNigeriaPrevalenceRetrospective StudiesCytokinesanorectalHIVHSV-2inflammationSTI

Identifiers

PMID36825536
PMCPMC10510689
OpenAlexW4321749601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.